International Journal of Clinical Research
International Journal of Clinical Research. 2025; 9: (3) ; 10.12208/j.ijcr.20250125 .
总浏览量: 73
1 大理大学临床医学院 云南大理
2 云南省第三人民医院内分泌科 云南昆明
*通讯作者： 桂莉,单位： 大理大学临床医学院 云南大理；朱宏,单位： 云南省第三人民医院内分泌科 云南昆明；
糖尿病足是糖尿病的严重并发症之一，给患者带来沉重负担。糖尿病足的发生与多种因素相关，包括神经病变、血管病变、感染和免疫功能低下等。而感染是引发足部坏疽、促使病情加剧的核心因素之一，采取切实有效的抗感染治疗是遏制病情恶化的关键举措。深入了解糖尿病足感染患者病原菌耐药特征并制定有效治疗策略至关重要。这有助于为患者制定个体化的治疗方案，从而提高治疗效果，降低截肢风险，改善患者预后与生活质量，同时也为合理使用抗菌药物、减少耐药菌的产生提供依据，在临床实践中具有重要的指导意义。本综述主要阐述目前国内外糖尿病足感染病原菌的耐药特征及其治疗的研究进展。
Diabetic foot is one of the serious complications of diabetes, which brings heavy burden to patients. The occurrence of diabetic foot is associated with many factors, including neuropathy, vascular disease, infection and immune dysfunction. Infection is one of the core factors that cause foot gangrene and aggravate the disease. Effective anti-infection treatment is the key measure to curb the deterioration of the disease. It is important to understand the characteristics of pathogen resistance in patients with diabetic foot infection and develop effective treatment strategies. It is helpful to develop an individualized treatment plan for patients, thereby improving the treatment effect, reducing the risk of amputation, improving the prognosis and quality of life of patients, and providing a basis for rational use of antibiotics and reducing the generation of drug-resistant bacteria, which has important guiding significance in clinical practice. This review mainly describes the current domestic and foreign research progress on drug resistance characteristics and treatment of pathogenic bacteria of diabetic foot infection.
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