International Journal of Clinical Research
International Journal of Clinical Research. 2024; 8: (12) ; 10.12208/j.ijcr.20240539 .
总浏览量: 123
辽宁省辽阳市灯塔市中心医院 辽宁辽阳
*通讯作者: 李淼,单位:辽宁省辽阳市灯塔市中心医院 辽宁辽阳;
目的 分析柴胡乌贝汤治疗胃溃疡(肝气犯胃型)的价值。方法 该研究总共纳入90例试验对象,均是2022年4月至2024年4月到医院诊治的胃溃疡(肝气犯胃型)患者,运用数字表随机排序法进行分组,分为对照组(常规西药治疗,共45例)与试验组(柴胡乌贝汤治疗,共45例)。对比两组的溃疡面积,观察两组的胃肠激素及炎症因子。结果 在胃溃疡面积、胃泌素及胆囊收缩素-33上,试验组低于对照组(P<0.05)。在C反应蛋白与肿瘤坏死因子-α水平上,试验组低于对照组(P<0.05)。结论 柴胡乌贝汤用于胃溃疡(肝气犯胃型)患者的效果良好,有助于缩小溃疡面积,调节胃泌素的表达水平,减轻炎症反应,临床可进一步推广应用。
Objective To analyze the value of Chaihu Wubei Decoction in the treatment of gastric ulcer (liver qi invading the stomach type). Methods A total of 90 subjects were included in this study, all of whom were patients with gastric ulcer (liver qi invading the stomach type) who came to the hospital for treatment from April 2022 to April 2024. They were randomly divided into a control group (conventional Western medicine treatment, a total of 45 cases) and an experimental group (Chaihu Wubei Decoction treatment, a total of 45 cases). The ulcer area between the two groups was compared, and the gastrointestinal hormones and inflammatory factors between the two groups were observed. Results The gastric ulcer area, gastrin and cholecystokinin-33 in the experimental group were lower than those in the control group (P < 0.05). In terms of C-reactive protein and tumor necrosis factor-α levels, the experimental group was lower than the control group (P < 0.05). Conclusion Chaihu Wubei decoction has a good effect on patients with gastric ulcer (liver qi attacking the stomach type), which helps to reduce the ulcer area, regulate the expression level of gastrin, and reduce the inflammatory response. It can be further promoted and applied clinically.
[1] 张迎迎,魏珂乐,丁鹤,等.胃镜联合三联疗法在胃溃疡患者中的治疗效果及对营养状态的影响研究[J].罕少疾病杂志,2024,31(10):68-70.
[2] 韩瑞瑞,穆亚娟,张璞,等.益生菌联合抗幽门螺杆菌治疗老年胃溃疡患者的临床疗效及对胃功能和肠道菌群的影响[J].贵州医药,2024,48(08):1218-1220.
[3] 李伟,张军锋,郭长江.疏肝和胃汤加减联合常规西药治疗胃溃疡患者的效果及对血清炎症因子的影响[J].慢性病学杂志,2024,25(08):1271-1274.
[4] 王文娜,张栓龙.双歧杆菌四联活菌片联合四联疗法对幽门螺杆菌阳性胃溃疡患者的临床观察[J].黑龙江医药科学,2024,47(04):102-105.
[5] 李佳泽,沈晓璞.健脾愈胃汤联合奥美拉唑对胃溃疡脾胃虚寒证患者溃疡面积、胃肠道症状及血清TFF2水平的影响[J].中国实验方剂学杂志,2024,30(19):133-138.
[6] 张铎.舒肝理气法治疗肝气犯胃型胃溃疡临床研究[J].光明中医,2021,36(01):67-68.
[7] 孙莉莉,杨成祥,王聪.肝胃百合汤加减辅助治疗老年肝气犯胃证胃溃疡患者的疗效评价[J].医学理论与实践,2023, 36(21):3642-3644.
[8] 翟张凯,刘茜茜.胃康灵联合替普瑞酮治疗肝气犯胃型胃溃疡疗效分析[J].中国烧伤创疡杂志,2024,36(01):70-73.
[9] 张萍.柴胡乌贝汤治疗胃溃疡(肝气犯胃型)的临床疗效观察[D].河南中医药大学,2020.
[10] 蒙晓冰,薛皓方,刘锐,等.半夏泻心汤加减治疗胃溃疡肝气犯胃证的疗效及对患者黏膜攻击和保护因子的影响[J].时珍国医国药,2020,31(03):624-627.