Observation of the role of nasal high flow oxygen therapy in the treatment of acute respiratory failure
经鼻高流量氧疗在急性呼吸衰竭治疗中的作用观察

摘要

目的 分析经鼻高流量氧疗在急性呼吸衰竭治疗中的临床疗效。方法 对我院2023年6月至2024年6月期间接收并治疗的60例急性呼吸衰竭患者的临床资料进行回顾性分析，根据治疗手段的差异分为参考组和实验组，每组30例，参考组采取无创正压通气治疗，实验组采取经鼻高流量氧疗。对比两组治疗24h后的呼吸频率及动脉血气指标、通气时间及器官切开或插管率以及并发症发生率。结果 相较于参考组，实验组的各项呼吸频率及动脉血气指标均显著更优（P<0.05）；实验组的通气时间短于参考组，气管切开或插管率显著低于参考组（P<0.05）；实验组的并发症发生率显著更低（P<0.05）。结论 经鼻高流量氧疗在急性呼吸衰竭治疗中表现出显著的临床效果，能够有效提升患者的呼吸功能并优化动脉血气水平，缩短通气时间，降低气管切开或插管率以及并发症发生率。

Abstract

Objective To analyze the clinical efficacy of nasal high-flow oxygen therapy in the treatment of acute respiratory failure.
Methods A retrospective analysis was conducted on the clinical data of 60 patients with acute respiratory failure who were received and treated in our hospital from June 2023 to June 2024. According to the differences in treatment methods, they were divided into a reference group and an experimental group, with 30 cases in each group. The reference group was treated with non-invasive positive pressure ventilation, and the experimental group was treated with nasal high-flow oxygen therapy. The respiratory frequency, arterial blood gas indicators, ventilation time, organ incision or intubation rate, and complication rate were compared between the two groups 24 hours after treatment.
Results Compared with the reference group, the respiratory frequency and arterial blood gas indicators of the experimental group were significantly better (P<0.05); the ventilation time of the experimental group was shorter than that of the reference group, and the tracheotomy or intubation rate was significantly lower than that of the reference group. The incidence of complications in the reference group (P<0.05); the experimental group was significantly lower (P<0.05).
Conclusion   Nasal high-flow oxygen therapy has significant clinical effects in the treatment of acute respiratory failure. It can effectively improve patients' respiratory function and optimize arterial blood gas levels, shorten ventilation time, reduce tracheotomy or intubation rates and the incidence of complications.