The effect of cognitive function training on the quality of life and psychological state of MCI patients
认知功能训练对MCI患者生活质量及心理状态的影响研究

摘要

目的 探讨认知功能训练对轻度认知障碍患者心理状态及生活质量的影响效果。方法 选取2021年2月~2021年9月陕西省人民医院收治的208例轻度认知障碍患者作为研究对象，根据随机数字表法分为对照组和干预组，各104例。对照组给予常规护理，干预组在此基础上进行为期12个月的认知功能训练干预，比较两组患者在干预前、干预后1个月、6个月，12个月时的认知功能（MMSE、MoCA）、心理状态（HAMD、HAMA）评分及生活质量（SF-36）量表得分，从而评估认知功能训练的疗效。结果 与干预前比较，干预12个月后两组患者认知功能（MMSE、MoCA）、心理状态（HAMD、HAMA）评分均下降，生活质量（SF-36）得分均升高（P＜0.05）；与对照组相比，观察组患者干预1、6、12个月后认知功能（MMSE、MoCA）得分更高，差异有统计学意义（P＜0.05）。干预6、12个月后心理状态（HAMD、HAMA）评分更低，差异有统计学意义（P＜0.05），干预12个月后生活质量（SF-36）得分更高，差异有统计学意义（P＜0.05）。结论 认知功能训练可以延缓MCI患者认知功能衰退进程，对其生活质量具有正向提升作用，且能够在一定程度上缓解患者焦虑、抑郁等不良情绪。

Abstract

Objective To investigate the effect of cognitive function training on the psychological state and quality of life of patients with mild cognitive impairment.
Methods A total of 208 patients with mild cognitive impairment admitted to Shaanxi Provincial People's Hospital from February 2021~September 2021 were selected as the study subjects, and they were divided into control group and intervention group, with 104 cases in each group. The control group was given routine nursing, and the intervention group underwent a 12-month cognitive function training intervention, and the cognitive function (MMSE, MoCA), psychological state (HAMD, HAMA) scores and quality of life (SF-36) scale scores were compared between the two groups before intervention, 1 month, 6 months after intervention, and 12 months, so as to evaluate the efficacy of cognitive function training.
Results Compared with the pre-intervention group, the scores of cognitive function (MMSE, MoCA) and psychological status (HAMD, HAMA) decreased and the scores of quality of life (SF-36) increased in both groups after 12 months of intervention (P<0.05), and compared with the control group, the scores of cognitive function (MMSE and MoCA) were higher after 1, 6 and 12 months of intervention in the observation group (P<0.05). After 6 and 12 months of intervention, the scores of psychological state (HAMD and HAMA) were lower and the difference was statistically significant (P<0.05), and the score of quality of life (SF-36) was higher after 12 months of intervention (P<0.05).
Conclusion   Cognitive function training can delay the decline of cognitive function in patients with MCI, have a positive effect on their quality of life, and can alleviate their anxiety, depression and other adverse emotions to a certain extent.