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国际临床研究杂志

International Journal of Clinical Research

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International Journal of Clinical Research. 2024; 8: (11) ; 10.12208/j.ijcr.20240475 .

Analysis of the therapeutic effect of butylphthalein combined with clopidogrel in the treatment of acute cerebral infarction
丁苯酞联合氯吡格雷治疗急性脑梗死疗效分析

作者: 杨超群 *

黄冈市人民医院 湖北黄冈

*通讯作者: 杨超群,单位:黄冈市人民医院 湖北黄冈;

引用本文: 杨超群 丁苯酞联合氯吡格雷治疗急性脑梗死疗效分析[J]. 国际临床研究杂志, 2024; 8: (11) : 97-99.
Published: 2024/11/24 14:29:33

摘要

目的 分析在治疗急性脑梗死采用丁苯酞联合氯吡格雷的治疗效果。方法 选取2023年6月至2024年4月在我院神经内科接受治疗的60例急性脑梗死患者作为观察对象,随机分为对照组(30例)和观察组(30例)。对照组采用氯吡格雷治疗,观察组采用丁苯酞联合氯吡格雷治疗。对比两组患者临床治疗效果、神经功能缺损程度及日常生活能力评分。结果 治疗后,观察组的临床效果显著优于对照组,神经功能缺损评分更低,日常生活能力更高。其差异均具有统计学意义(P<0.05)。结论 丁苯酞联合氯吡格雷在治疗急性脑梗死的治疗效果显著,能有效改善神经功能缺损,还可以提高患者日常生活能力。值得在临床推广应用。

关键词: 丁苯酞;吡格雷;急性脑梗死;治疗效果

Abstract

Objective To analyze the therapeutic effect of using butylphthalein combined with clopidogrel in the treatment of acute cerebral infarction.
Methods Sixty patients with acute elderly infarction who received treatment in the Department of Psychiatry of our hospital from June 2023 to April 2024 were selected as the observation subjects and randomly divided into a control group (30 cases) and an observation group (30 cases). The control group was treated with clopidogrel, while the observation group was treated with a combination of ibuprofen and clopidogrel. Compare the clinical treatment outcomes, degree of neurological deficits, and daily living ability scores between two groups of patients.
Results After treatment, the clinical effect of the observation group was significantly better than that of the control group, with lower scores of neurological deficits and higher daily living abilities. The differences were statistically significant (P<0.05).
Conclusion   The combination of ibuprofen and clopidogrel has significant therapeutic effects in the treatment of acute cerebral infarction, effectively improving neurological deficits and enhancing patients' daily living abilities. It is worth promoting and applying in clinical practice.

Key words: Butylphthalide; Pirgolay; Acute cerebral infarction; Treatment effect

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