Discussion on the preservation value of concentrated growth factor + deproteinbovine bone matrix sites
浓缩生长因子＋脱蛋白牛骨基质位点的保存价值探讨

摘要

目的 在拔牙位点保存中应用浓缩生长因子（concentrated growth factor，CGF）+脱蛋白牛骨基质（deproteinated bovine bone mineral，DBBM）所取得的成骨效果。方法 以2021年3月至2024年3月为研究范围，随机抽取需拔除患牙并接受位点保存后延期种植的40例患者为研究对象，按随机数字表法分组，每组20例。对照组、观察组拔牙后同期植入DBBM、CGF+DBBM，两组均覆盖海奥口腔修复膜，对比两组成骨效果。结果 两组位点保存术后6个月牙槽骨高度、宽度均较术前均明显降低（P < 0.05）；两组术后6个月牙槽骨高度变化无显著差异（P > 0.05），观察组术后6个月的牙槽嵴宽度吸收量较对照组明显更少（P < 0.05）；与对照组相比，观察组新生骨百分比更大，剩余移植材料平均面积百分比更少（P <0.05）。结论 应用CGF+DBBM位点保存对拔牙后牙槽骨体积、形态方面具有良好维持作用，与单用DBBM相比，CGF+DBBM的成骨效果更具优势。

Abstract

Objective: To achieve the osteogenic effect of concentrated growth factor (concentrated growth factor, CGF) + deproteinbovine bone matrix (deproteinated bovine bone mineral, DBBM) in the preservation of tooth extraction sites.
Methods: From March 2021 to March 2024 as the study scope, 40 patients with delayed implantation were randomly selected as the study subjects, with 20 patients in each group. In the control group and the observation group, DBBM and CGF + DBBM were implanted at the same time after tooth extraction. Both groups were covered with the Haiao oral prosthetic membrane, which compared the effect of the two component bone.
Results: The height and width of the alveolar bone were significantly lower (P <0.05); there was no significant difference in the height of the six months (P> 0.05), and the absorption was significantly less than the control group (P <0.05); compared with the control group, the percentage of new bone was greater and the average percentage area of the remaining graft material was less (P <0.05).
Conclusion  : With CGF + DBBM, site preservation can maintain alveolar bone volume and morphology. Compared with DBBM alone, CGF + DBBM showed better osteogenic effect.