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国际临床研究杂志

International Journal of Clinical Research

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International Journal of Clinical Research. 2024; 8: (8) ; 10.12208/j.ijcr.20240289 .

Experience of stage I surgical resection for spontaneous rupture and hemorrhage of primary liver cancer
原发性肝癌自发性破裂出血的I期手术切除治疗的体会

作者: 尹安1, 李文成2, 范斌3 *

1中国人民解放军郑州联勤保障中心临潼康复疗养中心 陕西西安

2贵州医科大学公共卫生与健康学院 贵州贵阳

3西北大学附属第一医院•西安市第一医院普外科 陕西西安

*通讯作者: 范斌,单位:西北大学附属第一医院•西安市第一医院普外科 陕西西安;

引用本文: 尹安, 李文成, 范斌 原发性肝癌自发性破裂出血的I期手术切除治疗的体会[J]. 国际临床研究杂志, 2024; 8: (8) : 20-22.
Published: 2024/8/19 2:14:31

摘要

目的 分析手术切除治疗原发性肝癌破裂出血的临床疗效。方法 选取2021年12月~2023年2月我院收治的原发性肝癌破裂出血患者,随机平均分为对照组与观察组,每组各45例,分别应用手术切除治疗与TACE治疗,对比两组疗效。结果 术后,两组总胆红素、白蛋白、血红蛋白、收缩压、舒张压水平对比(P<0.05)。同时,两组预后方面及并发症方面对比,差异无统计学意义(P>0.05)。结论 对于原发性肝癌自发性破裂出血患者应用TACE与手术切除治疗,疗效相差无几且效果较好。因此,可结合患者综合因素灵活选取适宜的治疗方式,有利于延长患者生存期。

关键词: 经导管动脉栓塞化疗;手术切除;原发性肝癌破裂大出血;并发症;血压

Abstract

Objective To analyze the clinical effect of surgical resection in the treatment of ruptured hemorrhage of primary liver cancer.
Methods Patients with rupture and hemorrhage of primary liver cancer admitted to our hospital from December 2021 to February 2023 were randomly divided into control group and observation group, with 45 cases in each group, respectively. The therapeutic effects of the two groups were compared.
Results After operation, the levels of total bilirubin, albumin, hemoglobin, systolic blood pressure and diastolic blood pressure were compared between two groups (P < 0.05). At the same time, there was no significant difference in prognosis and complications between the two groups (P > 0.05).
Conclusion   There is no difference between TACE and surgical resection in the treatment of spontaneous rupture and hemorrhage of primary liver cancer. Therefore, the appropriate treatment can be flexibly selected according to the comprehensive factors of patients, which is conducive to prolonging the survival of patients.

Key words: Transcatheter arterial embolization chemotherapy; Surgical excision; Primary liver cancer rupture massive hemorrhage; Complications; Blood pressure

参考文献 References

[1] 龚程,田银生,刘爽.不同时间窗手术治疗原发性肝癌自发破裂出血患者2年生存率比较[J].实用肝脏病杂志,2023, 26(2): 274-277

[2] 尹建云.早期TACE治疗无法手术切除原发性肝癌破裂出血的临床效果研究[J].中国科技期刊数据库 医药, 2023 (10):0084-0087

[3] 曹莉明,张勇学,梁志会,李亮,崔进国,石园园,刘佩,汪景洲,陈静.三种不同方法联合TACE治疗原发性肝癌合并食管胃底静脉曲张破裂出血的临床效果[J].医学影像学杂志,2023,33(10):1814-1820

[4] 徐庆娜,李芳.围术期早期快速康复外科护理对原发性肝癌患者胃肠道功能恢复及生活质量的影响[J].浙江医学,2023,45(8):877-880

[5] 武思彤,吕天石,曹守金,刘泽川,姚航,范思源,谢勇,关海涛,宋莉,佟小强,邹英华,王健.TIPS序贯TACE、靶向和/或免疫治疗BCLC D期原发性肝细胞癌伴严重门静脉高压并发症[J].中国介入影像与治疗学,2023,20(1):12-16

[6] 龚杰,高峰畏,雷泽华,蒋康怡,谢青云,赵欣.沿肝静脉主干入路的开腹解剖性肝脏切除术治疗原发性肝癌的疗效及安全性[J].现代肿瘤医学,2023,31(14):2666-2672

[7] 雷碧波,樊飞,张明强,王小琦.超声引导下腹横肌平面阻滞联合喉罩通气在原发性肝癌患者加速康复外科中的有效性和安全性[J].介入放射学杂志,2023,32(2):149-153

[8] 万文武,张瑜,丁兵,张勇,凌俊,方程,何攀,谢飞,蒋辉.肝切除术与TACE治疗原发性肝癌破裂出血疗效的倾向评分匹配分析[J].中国普通外科杂志,2022,31(1):22-30.