The therapeutic effect of levothyroxine on subclinical hypothyroidism
左旋甲状腺素治疗亚临床甲状腺功能减退的疗效研究

摘要

目的 探析左旋甲状腺素治疗亚临床甲状腺功能减退的临床效果和实用价值。方法 选择我院于2022年10月至2023年10月期间收治的80例亚临床甲状腺功能减退患者作为研究对象。将患者按照治疗方法的不同随机分为对照组（40例，使用常规治疗）和研究组（40例，实施左旋甲状腺素治疗）。对两组患者的血脂指标水平与治疗效果进行对比分析。结果 两组患者在治疗后均取得一定效果，研究组患者治疗总有效度高于对照组，TC、TG、LDL–C相对于对照组更低，HDL–C水平对比无明显差异。结论 左旋甲状腺素治疗亚临床甲状腺功能减退具有显著的临床效果，能够有效改善患者的血脂指标水平，提高患者的治疗效果，有较高的安全性和临床应用价值。

Abstract

Objective To explore the clinical efficacy and practical value of levothyroxine in the treatment of subclinical hypothyroidism.
Methods 80 subclinical hypothyroidism patients admitted to our hospital from October 2022 to October 2023 were selected as the study subjects. Patients were randomly divided into a control group (40 cases, treated with conventional therapy) and a study group (40 cases, treated with levothyroxine) according to different treatment methods. Compare and analyze the levels of blood lipid indicators and treatment outcomes between two groups of patients.
Results Both groups of patients achieved certain results after treatment. The total effectiveness of treatment in the study group was higher than that in the control group, with lower levels of TC, TG, and LDL-C compared to the control group. There was no significant difference in HDL-C levels compared to the control group.
Conclusion   The treatment of subclinical hypothyroidism with levothyroxine has significant clinical effects, can effectively improve the level of blood lipid indicators in patients, enhance the treatment effect of patients, and has high safety and clinical application value.