Current status of clinical application research on pentylethoxyquine hydrochloride
盐酸戊乙奎醚临床应用研究现状

摘要

盐酸戊乙金醚（penchyc lidine hydrochlor ide）是我国军事科学院自主研究的长效抗胆碱药，义名长托宁，化学结构为3-（2-环戊转-2-羟基-2-苯基乙氧基）。盐酸戊乙奎醚对M受体具有高度选择的作用，在抗胆碱及抑制腺体分泌方面发挥着高效而稳定的优势。在关于该药物临床应用的研究中，发现这一药物在多种疾病临床治疗中均展现出突出的应用价值。对此，本文中将收集整理有关盐酸戊乙奎醚临床应用的研究成果，对该药物的药代动力学与药效作用机制，以及该药物在各领域临床中实际应用的情况进行完整的论述，形成对这一药物临床应用发展更为全面的认知，为实际临床中该药物的推广应用以及后续相关课题研究提供更全面的理论参考资料。

Abstract

Penchyc lidine hydrochlor ide is a long-acting anticholinergic drug independently researched by Chinese Academy of Military Sciences. It is named Changtonin and has a chemical structure of 3- (2-cyclopentyl-2-hydroxy-2-phenylethoxy). Penehyclidine hydrochloride has a highly selective effect on M receptors, and plays an efficient and stable advantage in anticholine and inhibiting glandular secretion. In the study on the clinical application of this drug, it was found that this drug has shown outstanding application value in the clinical treatment of a variety of diseases. In this regard, this paper will collect and sort out the research results related to the clinical application of penehyclidine hydrochloride, and conduct a complete discussion on the pharmacokinetics and pharmacodynamic mechanism of this drug, as well as the actual clinical application of this drug in various fields, so as to form a more comprehensive understanding of the clinical application and development of this drug. To provide more comprehensive theoretical reference for the promotion and application of the drug in practice and the subsequent research on related topics.