To analyze the clinical efficacy of omeprazole combined with aluminum phosphate gel in the treatment of gastroesophageal reflux disease in children
分析奥美拉唑联合磷酸铝凝胶治疗小儿胃食管反流病的临床疗效

摘要

目的 分析对小儿胃食管反流病患者应用奥美拉唑联合磷酸铝凝胶治疗的治疗作用。方法 抽选2021年7月-2023年7月于我院就诊的小儿胃食管反流病患者72例，以分层随机分36例为对照组实施奥美拉唑治疗，另外36例为观察组增加磷酸铝凝胶治疗，对比两组治疗前后的食管反流治疗效果；对比两组治疗前后的血清相关检查数值；结果 护理前食管反流各项指标以及血清相关检查数值差异不显著，P﹥0.05,护理后观察组各项指标优于对照组，差异显著，P﹤0.05。结论 对小儿胃食管反流病患者实施奥美拉唑联合磷酸铝凝胶的治疗效果较好，可减少反流次数，改善食管反流情况，同时生化血清指标，进一步控制改善疾病症状。

Abstract

Objective To analyze the therapeutic effect of omeprazole combined with aluminum phosphate gel on children with gastroesophageal reflux disease.
Methods 72 children with gastroesophageal reflux disease who visited our hospital from July 2021 to July 2023 were selected. 36 cases were randomly divided into the control group and the observation group. The other 36 cases were treated with aluminum phosphate gel. The therapeutic effects of esophageal reflux before and after treatment were compared between the two groups; Compare the serum related test values before and after treatment between the two groups;
Results There was no significant difference in various indicators of esophageal reflux and serum related test values before nursing, with p>0.05. After nursing, the observation group had better indicators than the control group, with a significant difference, P<0.05.
Conclusion   Omeprazole combined with aluminum phosphate gel is effective in the treatment of children with gastroesophageal reflux disease, which can reduce the number of reflux, improve the situation of esophageal reflux, and biochemical serum indicators to further control and improve the symptoms of the disease.