International Journal of Clinical Research
International Journal of Clinical Research. 2024; 8: (6) ; 10.12208/j.ijcr.20240243 .
总浏览量: 188
1 道真仡佬族苗族自治县中医医院 贵州遵义
2 贵州中医药大学第一附属医院 贵州贵阳
*通讯作者： 杨轩,单位： 道真仡佬族苗族自治县中医医院 贵州遵义；
目的 研究消疣汤联合电、光疗法对肛管CA疗效及血清iNOS、HIF-1α。方法 选取肛管尖锐湿疣患者60例，随机均分为对照组以及观察组，对照组实施电离子联合光动力疗法，观察组实施消疣汤联合电离子以及光动力疗法治疗，对比治疗效果。结果 观察组治疗效果优于对照组（P<0.05）。结论 消疣汤联合电、光疗法对肛管尖锐湿疣患者实施治疗可以改善血清iNOS、HIF-1α指标，改善治疗效果，改善复发率。
Objective To study the effect of Xiaoverruca decoction combined with electric and light therapy on anorectal CA and serum iNOS and HIF-1α. Methods 60 patients with anal canal condyloma acuminatum were randomly divided into control group and observation group. The control group was treated with electroion combined with photodynamic therapy, and the observation group was treated with Xiaowart decoction combined with electroion combined with photodynamic therapy, and the therapeutic effect was compared. Results The treatment effect of observation group was better than that of control group (P<0.05). Conclusion Xiaoverruca Decoction combined with electric and light therapy can improve the serum iNOS and HIF-1α, improve the therapeutic effect and improve the recurrence rate of patients with anal condyloma acuminatum.
[1] 杜秋燕,许慧芳,王新杰,等.5-氨基酮戊酸光动力疗法联合湿疣汤熏洗治疗女性复发性尖锐湿疣的疗效分析[J].中国中西医结合皮肤性病学杂志,2023,22(02):141-144.
[2] 王勇超,王永亮,叶科富.燥湿解毒除疣方加减配合手术治疗肛周尖锐湿疣的疗效及对血清VEGF、IL-1β、IL-2水平的影响[J].四川中医,2023,41(04):162-165.
[3] 赵文斌,陈淑慧,王哲.四妙丸联合重组人干扰素α-2b凝胶治疗尖锐湿疣的临床疗效观察及HPV检测分析[J].中国中西医结合皮肤性病学杂志,2023,22(01):56-58.
[4] 中华医学会皮肤性病学分会性病学组,中国医师协会皮肤科分会性病亚专业委员会.尖锐湿疣诊疗指南(2014)[J]. 中华皮肤科杂志,2014,47(8):598-599.
[5] 吴军、王波.中西医临床外科学[J]中国医药科技出版社,2012: 488.
[6] 王艳芳,万长兰,陈晓吟,等 艾拉光动力治疗尖锐湿疣的疗效观察及护理体会. 国际医药卫生导报, 2019 ,25 (19) : 3300-3302.
[7] 王瑞华,胡勇,郑秀芬,等.光动力联合重组人干扰素α2b栓治疗肛管尖锐湿疣的疗效观察[J].2020,(13).
[8] 景伟芳,周娜娜,刘雪,等.尖锐湿疣复发患者HPV基因分型的分布情况及关系分析[J].2018,(5).