Clinical application of C13-urea breath test to detect Helicobacter pylori infection in children
C13-尿素呼气试验检测儿童幽门螺杆菌感染临床应用价值研究

摘要

目的 研究儿童幽门螺杆菌感染经C13-尿素呼气试验检测的效果，并总结其应用价值。方法 对2023年1月-2024年1月我院进行幽门螺杆菌感染检查的儿童100例作为研究对象，对其进行C13-尿素呼气试验检测，获取检测结果，并进行血清幽门螺杆菌抗体检测，对C13-尿素呼气试验检测准确性进行评估。结果 观察研究数据，C13- 尿素呼气试验儿童幽门螺杆菌感染检出25例，血清幽门螺杆菌抗体检测感染检出44例，两项检验结果统计学对比无差异性（P>0.05）；分析C13- 尿素呼气试验检验效能，敏感性24/25（96.00%）、特异性55/75（73.33%）、准确性79/100（79.00%）。结论 经研究可见，C13- 尿素呼气试验检测儿童幽门螺杆菌感染检出率较高，可提升检测准确性，同时敏感性、特异性、准确性较高，可为儿童幽门螺杆菌感染者提供进一步准确治疗，为疾病治疗及治疗效果提供有利保障，值得检验可广泛应用。

Abstract

Objective To investigate the detection of Helicobacter pylori infection in children by C13-urea breath test, and to summarize its application value.
Methods 100 children with Helicobacter pylori infection in our hospital from January 2023 to January 2024 were selected as research objects. C13-urea breath test was performed on them to obtain the test results, and serum Helicobacter pylori antibody was detected to evaluate the detection accuracy of C13-urea breath test.
Results According to the study data, 25 cases of Helicobacter pylori infection were detected by C13-urea breath test and 44 cases were detected by serum Helicobacter pylori antibody test. There was no statistical difference between the two test results (P>0.05). The sensitivity of C13-urea breath test was 24/25 (96.00%), specificity 55/75 (73.33%) and accuracy 79/100 (79.00%).
Conclusion   The study shows that C13-urea breath test has a high detection rate of Helicobacter pylori infection in children, which can improve the detection accuracy. At the same time, it has a high sensitivity, specificity and accuracy, which can provide further accurate treatment for children infected with Helicobacter pylori, and provide favorable guarantee for disease treatment and therapeutic effect. It is worthy of testing and can be widely used.