Intervention effect of TCM acupoint application combined with ondansetron hydrochloride on gastrointestinal response in neoadjuvant patients with advanced lung cancer
中药穴位贴敷联合盐酸昂丹司琼对晚期肺癌新辅助患者胃肠道反应的干预效果

摘要

目的 研讨中药穴位贴敷联合盐酸昂丹司琼对晚期肺癌新辅助患者胃肠道反应的干预效果。方法 选取2022年5月至2023年12月期间，我机构300例晚期肺癌新辅助治疗的病例，运用随机数表法将这些患者均分为两组，每组150人。一组作为对照组，接受盐酸昂丹司琼治疗；另一组为实验组，采用中药穴位贴敷结合盐酸昂丹司琼进行治疗。之后比较两组患者的恶心呕吐发生率、食欲状况以及止吐治疗的效果。结果 实验组疗效数值比对照组高，差异显著，P＜0.05；实验组恶心呕吐发生率比对照组低，P＜0.05。结论 晚期肺癌新辅助患者实施中药穴位贴敷联合盐酸昂丹司琼治疗方案可有效干预恶心呕吐发生，能够改善患者食欲状况，可提升止吐效果，值得临床借鉴。

Abstract

Objective To investigate the intervention effect of acupoint application of Chinese medicine combined with ondansetron hydrochloride on gastrointestinal reactions in neoadjuvant patients with advanced lung cancer.
Methods From May 2022 to December 2023, 300 cases of advanced lung cancer neoadjuvant therapy in our institution were selected, and these patients were divided into two groups with 150 patients in each group by random number table method. One group was treated with ondansetron hydrochloride as control group. The other group was the experimental group, treated with Chinese medicine acupoint application combined with ondansetron hydrochloride. The incidence of nausea and vomiting, appetite status and the effect of antiemetic therapy were compared between the two groups.
Results The therapeutic value of the experimental group was higher than that of the control group, the difference was significant (P < 0.05); The incidence of nausea and vomiting in the experimental group was lower than that in the control group, P < 0.05.
Conclusion   The application of Chinese medicine acupoint application combined with ondansetron hydrochloride in the treatment of advanced lung cancer patients can effectively intervene in the occurrence of nausea and vomiting, improve the appetite status of patients, and enhance the effect of anti-vomiting, which is worthy of clinical reference.