Study on the effect of pharmacists participating in pain management of knee replacement under accelerated rehabilitation
加速康复下药师参与膝关节置换术疼痛管理的效果研究

摘要

目的 分析对接受膝关节置换术的患者实施加速康复下药师参与的疼痛管理的应用效果。方法 抽取2022年11月-2023年11月期间在我院择期接受膝关节置换术治疗的患者70例，以随机信封法分组，术后接受常规疼痛管理的患者为对照组，共35例，术后接受药师参与疼痛管理的患者为观察组，共35例。对比两组术后不同时间节点疼痛程度、镇痛药物不合理使用率、镇痛药所致不良反应发生率。结果 （1）术后12h，两组患者NRS评分对比差异不明显（P＞0.05）；术后24h、2d、3d、5d、7d时，观察组NRS评分均更低（P＜0.05）；（2）观察组镇痛药物不合理使用率为8.57%，低于对组（P＜0.05）；（3）观察组镇痛药物所致不良反应发生率为5.71%，低于对照组（P＜0.05）。结论 对膝关节置换术患者实施加速康复下药师参与的疼痛管理可缓解患者疼痛水平，降低镇痛药物不合理用药率，降低因不合理用药所致的不良反应发生风险。

Abstract

Objective To analyze the application effect of pain management with pharmacist participation in accelerated rehabilitation for patients undergoing knee replacement surgery.
Methods A total of 70 patients who underwent elective knee replacement surgery in our hospital from November 2022 to November 2023 were selected and divided into two groups using a random envelope method. Patients who received routine pain management after surgery were selected as the control group, with a total of 35 cases. Patients who received pain management with the participation of pharmacists after surgery were selected as the observation group, with a total of 35 cases. Compare the degree of pain, irrational use of analgesics, and incidence of adverse reactions caused by analgesics between two groups at different postoperative time points.
Results (1) 12 hours after surgery, there was no significant difference in NRS scores between the two groups of patients (P>0.05); At 24 hours, 2 days, 3 days, 5 days, and 7 days after surgery, the observation group had lower NRS scores (P<0.05);(2) The irrational use rate of analgesic drugs in the observation group was 8.57%, lower than that in the control group (P<0.05); (3) The incidence of adverse reactions caused by analgesic drugs in the observation group was 5.71%, lower than that in the control group (P<0.05).
Conclusion   Implementing pain management involving pharmacists in accelerated rehabilitation for patients undergoing knee replacement surgery can alleviate patient pain levels and reduce the incidence of irrational use of analgesics, reduce the risk of adverse reactions caused by irrational drug use.