International Journal of Clinical Research
International Journal of Clinical Research. 2024; 8: (7) ; 10.12208/j.ijcr.20240244 .
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暨南大学附属广州红十字会医院普通外科 广东广州
*通讯作者： 王百林,单位：暨南大学附属广州红十字会医院普通外科 广东广州；
慢性肝病早期可以逆转，但晚期的肝硬化和肝细胞癌严重影响患者生活质量，因此对于防治肝病药物的研究一直是热点。传统中药用于防治肝病历史悠久，具有其独特的优势。黄芪甲苷是传统中药黄芪的主要化学成分和生物活性成分，在防治肝纤维化、非酒精性脂肪性肝病、药物性肝损伤、肝细胞癌等肝病中发挥着重要作用。本综述对黄芪甲苷在防治常见肝病的相关国内外文献进行梳理，以期为该中药单体深入研究和临床应用提供文献依据和研究思路。
While chronic liver disease can be reversed in its early stages, advanced cirrhosis and hepatocellular carcinoma have a serious impact on patients' quality of life, leading to a flurry of research into drugs to combat liver disease. Traditional Chinese medicine has a long history in the prevention and treatment of liver diseases and has its unique advantages. Astragaloside IV is the main chemical and bioactive component of the traditional Chinese medicine Astragalus, which plays an important role in the prevention and treatment of hepatic fibrosis, non-alcoholic fatty liver disease, drug-induced liver injury, hepatocellular carcinoma and other liver diseases. This review summaries the domestic and international literature on the prevention and treatment of common liver diseases with Astragaloside IV, in order to provide literature basis and research ideas for the in-depth research and clinical application of this traditional Chinese medicine monomer.
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