The clinical effect of metoprolol combined with amiodarone in the treatment of arrhythmia
美托洛尔联合胺碘酮治疗心律失常的临床效果

摘要

目的 研究心律失常采取美托洛尔、胺碘酮联合治疗的临床疗效。方法 选取2021年8月-2023年8月于本院治疗的心律失常患者（90例），用数字随机表法均分为2组，对照组（胺碘酮治疗）、观察组（美托洛尔、胺碘酮联合治疗）各为45例。对2组患者分别采用不同治疗方案的治疗效果比较。结果 组间疗效相比，观察组患者的治疗总有效率明显高出对照组，数据差异具有统计学意义（P＜0.05）。两组治疗后的心动过速发作次数与室性期前收缩发作次数较治疗前明显降低，观察组治疗后的发作次数低于对照组，具有统计学意义（P＜0.05）；而两组治疗后的QTs期间比治疗前提高，且观察组治疗后的QTs期间高于对照组，具有统计学意义（P＜0.05）。结论 对心律失常患者采取美托洛尔、胺碘酮联合治疗的效果良好，可有效改善患者的心功能，有利于提高疗效。

Abstract

Objective To study the clinical efficacy of combined treatment with metoprolol and amiodarone for arrhythmia.
Methods Ninety patients with arrhythmia who were treated in our hospital from August 2021 to August 2023 were selected and randomly divided into two groups using a digital random table method. The control group (treated with amiodarone) and the observation group (treated with metoprolol and amiodarone combination) each had 45 cases. Compare the therapeutic effects of different treatment plans on two groups of patients.
Results Compared with the control group, the total effective rate of treatment in the observation group was significantly higher, and the data difference was statistically significant (P<0.05). The number of tachycardia attacks and ventricular premature contractions in the two groups after treatment was significantly reduced compared to before treatment. The number of attacks in the observation group after treatment was lower than that in the control group, with statistical significance (P<0.05); The QTs period after treatment in both groups increased compared to before treatment, and the QTs period after treatment in the observation group was higher than that in the control group, with statistical significance (P<0.05).
Conclusion   The combined treatment of metoprolol and amiodarone for patients with arrhythmia has a good effect and can effectively improve their cardiac function, which is beneficial for improving the therapeutic effect.