Study on the therapeutic effect of combination of oseltamivir phosphate and prednisolone anti-inflammatory oral solution in the treatment of pediatric influenza virus infection
磷酸奥司他韦联合蒲地蓝消炎口服液治疗小儿流感病毒感染治疗效果研究

摘要

目的 分析对小儿流感病毒感染患者应用磷酸奥司他韦联合蒲地蓝消炎口服液治疗的效果。方法 抽选2021年3月-2023年于我院就诊的小儿流感病毒感染患者68例随机分34例为对照组接受磷酸奥司他韦治疗，观察组35例则增加蒲地蓝消炎口服液，对比两组临床症状改善时间和不良反应；结果 治疗后，观察组临床症状改善时间优于对照组，差异显著，P﹤0.05，同时不良反应对比上，两组不良反应差异小，无显著意义，P﹥0.05，结论 对小儿流感病毒感染患者实施磷酸奥司他韦联合蒲地蓝消炎口服液治疗效果较好，加快患儿症状改善，利于躯体舒适，同时治疗安全性较高，无明显不良反应。

Abstract

Objective To analyze the therapeutic effect of using oseltamivir phosphate combined with prednisolone anti-inflammatory oral solution on children with influenza virus infection.
Methods 68 pediatric patients with influenza virus infection who visited our hospital from March 2021 to 2023 were randomly divided into a control group of 34 cases receiving treatment with oseltamivir phosphate, and an observation group of 35 cases receiving treatment with Pudillan anti-inflammatory oral solution. The clinical symptom improvement time and adverse reactions of the two groups were compared;
Results After treatment, the improvement time of clinical symptoms in the observation group was significantly better than that in the control group, with a difference of P<0.05. At the same time, the difference in adverse reactions between the two groups was small and not significant, with P>0.05.
Conclusion   The combination of oseltamivir phosphate and prednisolone anti-inflammatory oral solution has a good therapeutic effect on children with influenza virus infection, accelerates the improvement of symptoms in children, benefits physical comfort, and is relatively safe to treat, with no obvious adverse reactions.