The efficacy of esomeprazole and omeprazole in the treatment of gastric ulcers
埃索美拉唑与奥美拉唑治疗胃溃疡的效果

摘要

目的 分析埃索美拉唑与奥美拉唑治疗胃溃疡的效果。方法 将我院于2023年1月-2023年12月收治的84例胃溃疡患者作为研究对象，通过随机数字表法分为对照组与观察组，每组各42例。对照组应用奥美拉唑治疗，观察组应用埃索美拉唑治疗，对比两组治疗效果。结果 观察组在采用急埃索美拉唑治疗后，其临床症状改善评分、炎性因子水平、不良反应发生率均低于对照组，组间差异显著（P＜0.05）。结论 相较于奥美拉唑，埃索美拉唑治疗胃溃疡效果较好，可有效改善患者相关症状，减轻其炎性反应，且安全性较高。

Abstract

Objective To analyze the efficacy of esomeprazole and omeprazole in the treatment of gastric ulcers.
Methods 84 patients with gastric ulcers admitted to a hospital from January 2023 to December 2023 were selected as the study subjects. They were randomly divided into a control group and an observation group using a random number table method, with 42 cases in each group. The control group was treated with omeprazole, while the observation group was treated with esomeprazole. The therapeutic effects of the two groups were compared.
Results After treatment with emergency esomeprazole, the clinical symptom improvement score, inflammatory factor levels, and incidence of adverse reactions in the observation group were lower than those in the control group, with significant differences between groups (P<0.05).
Conclusion   Compared to omeprazole, esomeprazole has a better therapeutic effect on gastric ulcers, can effectively improve patient related symptoms, alleviate inflammatory reactions, and is relatively safe.