[email protected]

国际临床研究杂志

International Journal of Clinical Research

您当前位置:首页 > 精选文章

International Journal of Clinical Research. 2024; 8: (3) ; 10.12208/j.ijcr.20240097 .

Clinical efficacy of Nimodipine combined with Rosuvastatin calcium tablets in the treatment of hypertensivecerebral hemorrhage
尼莫地平联合瑞舒伐他汀钙片治疗高血压脑出血的临床疗效研究

作者: 徐春雨 *

山东医学高等专科学校 山东临沂

*通讯作者: 徐春雨,单位:山东医学高等专科学校 山东临沂;

引用本文: 徐春雨 尼莫地平联合瑞舒伐他汀钙片治疗高血压脑出血的临床疗效研究[J]. 国际临床研究杂志, 2024; 8: (3) : 55-57.
Published: 2024/3/26 15:38:23

摘要

目的 研究尼莫地平联合瑞舒伐他汀钙片治疗高血压脑出血的临床疗效。方法 将2022年01月-2023年10月间我院收治的高血压脑出血患者100例随机分为对照组和实验组,并分析不同治疗方式的应用效果。结果 实验组患者其对神经功能、水肿体积以及血肿量的改善均优于对照组,对比炎性因子水平,实验组优于对照组,P<0.05。并且两组患者的不良反应发生率没有明显的差异性,P>0.05。结论 尼莫地平联合瑞舒伐他汀钙片的应用能够改善高血压脑出血患者的临床症状,控制疾病的发展,使其神经功能得到良好的调节,患者机体的炎性因子水平明显降低,提高患者的恢复速度和效果,改善患者的生活质量。

关键词: 尼莫地平;瑞舒伐他汀钙片;高血压脑出血;联合治疗;临床疗效

Abstract

Objective To study the clinical efficacy of Nimodipine combined with rosuvastatin calcium tablets in the treatment of hypertensive intracerebral hemorrhage.
Methods 100 patients with hypertensive cerebral hemorrhage admitted to our hospital from January 2022 to October 2023 were randomly divided into control group and experimental group, and the application effects of different treatment methods were analyzed.
Results The improvement of nerve function, edema volume and hematoma volume in experimental group was better than that in control group, compared with the level of inflammatory factors, the experimental group was better than the control group, P < 0.05. There was no significant difference in the incidence of adverse reactions between the two groups (P > 0.05).
Conclusion   Nimodipine combined with rosuvastatin calcium tablets can improve the clinical symptoms of patients with hypertensive intracerebral hemorrhage, control the development of the disease, make the neurological function of the patients be well regulated, the level of inflammatory factors in the patients is significantly reduced, improve the recovery speed and effect of patients, and improve the quality of life of patients.

Key words: Nimodipine; Rosuvastatin calcium tablets; Hypertensive cerebral hemorrhage; Combination therapy; Clinical effect

参考文献 References

[1] 郭宗坤.瑞舒伐他汀钙联合阿司匹林、尼莫地平治疗短暂性脑缺血发作患者的效果[J].中国民康医学,2023,35 (20): 30-33. 

[2] 苏维海.尼莫地平联合瑞舒伐他汀钙片治疗高血压性脑出血患者的效果及对神经功能、炎症因子的影响[J].智慧健康,2023,9(21):132-136. .

[3] 方曙平,宋熙文.尼莫地平联合瑞舒伐他汀钙片治疗高血压脑出血的临床疗效[J].中西医结合心脑血管病杂志,2022,20(8):1509-1512. .

[4] 赵楠.尼莫地平联合瑞舒伐他汀钙片治疗高血压脑出血的临床疗效比较[J].临床医药文献电子杂志,2022,9(6): 64-66.

[5] 王婵,王胜,李明磊.瑞舒伐他汀钙联合阿司匹林肠溶片及尼莫地平对短暂性脑缺血发作患者颈动脉斑块和血清Lp-PLA2、MMP-9、Hcy水平的影响[J].中国实用医刊,2022,49(8):109-112. 

[6] 梁道桥,汤树洪,覃重桥,等.瑞舒伐他汀联合尼莫地平对轻度脑小血管病性认知功能损害的疗效研究[J].世界最新医学信息文摘,2021,21(98):241-242,244. 

[7] 董歌.瑞舒伐他汀钙联合阿司匹林肠溶片、尼莫地平治疗短暂性脑缺血发作的疗效[J].检验医学与临床,2021, 18(19):2894-2897. 

[8] 张继红,孙跃辉.瑞舒伐他汀对短暂性脑缺血发作患者血脂水平及颈动脉斑块的影响观察研究[J].健康之友, 2020,(2):117.