International Journal of Clinical Research
International Journal of Clinical Research. 2024; 8: (3) ; 10.12208/j.ijcr.20240090 .
总浏览量: 162
中国人民解放军联勤保障部队第九二〇医院
*通讯作者： 徐永清,单位：中国人民解放军联勤保障部队第九二〇医院；
地舒单抗是治疗成年人骨骼疾病的一种有价值和安全的疗法，并已获得法规批准用于治疗骨质疏松症和骨转移。然而，由于缺乏高质量的儿童前瞻性研究，地舒单抗未被批准用于儿科。本综述旨在描述和讨论地舒单抗治疗儿童骨病的益处和缺点，并总结目前对地舒单抗在儿童中作用的认识。
Denosumab is a valuable and safe treatment for skeletal diseases in adults, and has been approved by regulations for the treatment of osteoporosis and bone metastasis. However, due to the lack of high-quality prospective studies in children, denosumab has not been approved for pediatric use. This review aims to describe and discuss the benefits and disadvantages of denosumab in the treatment of bone diseases in children, and to summarize the current understanding of the role of denosumab in children.
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