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国际临床研究杂志

International Journal of Clinical Research

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International Journal of Clinical Research. 2023; 7: (8) ; 10.12208/j.ijcr.20230292 .

Advance in laboratory diagnosis of invasive pulmonary aspergillosis
侵袭性肺曲霉病实验室诊断研究进展

作者： 曹文 *

湖北中医学院药大学医学检验与技术学院 湖北武汉

*通讯作者： 曹文,单位：湖北中医学院药大学医学检验与技术学院 湖北武汉；

引用本文: 曹文 侵袭性肺曲霉病实验室诊断研究进展[J]. 国际临床研究杂志, 2023; 7: (8) : 31-35.
Published: 2023/8/20 18:13:35

摘要

侵袭性肺曲霉病（Invasive pulmonary aspergillosis，IPA）是指曲霉菌侵入肺组织而引起的感染性疾病，治疗困难，发病率、死亡率和治疗费用均较高。且临床表现与其他病原感染较为相似，早期诊断和及时治疗是病人预后良好的关键。本文对侵袭性肺曲霉病的相关实验诊断技术的研究进展从曲霉菌的培养和鉴定、相关生物标志物、分子生物学检测技术三个方面进行了总结。

关键词： 侵袭性肺曲霉病；感染；念珠菌；检测方法

Abstract

Invasive pulmonary aspergillosis (IPA) is an infectious disease caused by Aspergillosis invading lung tissue, which is difficult to treat and has high morbidity, mortality and treatment cost. The clinical manifestations are similar to other pathogenic infections. Early diagnosis and timely treatment are the key to a good prognosis. In this paper, the research progress of experimental diagnosis of invasive pulmonary aspergillus disease was summarized from three aspects: culture and identification of aspergillus, related biomarkers and molecular biological detection techniques.

Key words： Invasive pulmonary aspergillosis; Infection; Candida; Detection method

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