International Journal of Clinical Research
International Journal of Clinical Research. 2023; 7: (7) ; 10.12208/j.ijcr.20230279 .
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1 成都医学院附属妇女儿童医院儿童健康中心 四川成都
2 四川省妇幼保健院儿童健康中心 四川成都
*通讯作者： 雷勋明,单位： 四川省妇幼保健院儿童健康中心 四川成都；
神经信号转导通路可以通过不同的方式、途径等对呼吸道的相关细胞组织起到一定的影响作用，研究发现其参与了支气管哮喘的气道炎症和气道重塑，本文综述了p38 MAPK/NF-kB信号通路在支气管哮喘发病机制中的研究进展，进一步了解神经信号转导通路有助于探索哮喘的发生机制，为哮喘的临床治疗提供更精确更新颖的靶点，对未来研究新药、提高相关疾病临床疗效均有重要意义。
The neural signal transduction pathway can play a certain role in influencing the relevant cell tissues of the respiratory tract through different ways and pathways, thus inducing the occurrence and development of bronchial asthma. This article reviews the research progress of p38 MAPK/NF kB signal pathway in the pathogenesis of bronchial asthma, and further understands the neural signal transduction pathway is helpful to explore the pathogenesis of asthma, to provide more accurate targets for the clinical treatment of asthma, which is of great significance for the future research of new drugs and the improvement of clinical efficacy of related diseases.
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