Clinical value of serum Cystatin C and coagulation function test in patients with acute cerebral infarction
血清胱抑素C及凝血功能检验在急性脑梗死患者中的临床应用价值

摘要

目的 分析急性脑梗死（ACI）患者中采取血清胱抑素C（CysC）、凝血功能检验的价值。方法 选取2020年8月至2021年9月收治的ACI患者50例为观察组，选取相同时期健康体检者50例为对照组，均实施CysC、凝血功能检验，对比两组及不同梗死类型、不同预后患者的检验结果。结果 观察组/完全性/死亡组患者的FIB水平、CysC水平均高于对照组/进展型/存活型（P<0.05）；观察组/完全型/死亡组患者APTT水平、TT水平、PT水平均低于对照组（P<0.05）；在对凝血功能、CysC水平影响的因素中，预后、疾病类型均为独立危险因素（P<0.05）。结论 ACI患者利用CysC、凝血功能诊断存在的效果良好，可在医师对病情和预后评估分析中提供有价值依据。

Abstract

Objective To analyze the value of serum Cystatin C (CysC) and blood coagulation function test in patients with acute cerebral infarction (ACI).
Methods 50 ACI patients admitted from August 2020 to September 2021 were selected as the observation group, and 50 healthy individuals who underwent physical examinations during the same period were selected as the control group. CysC and coagulation function tests were performed on both groups, and the test results of the two groups and patients with different infarction types and prognosis were compared.
Results The FIB and CysC levels in the observation group/complete/death group were higher than those in the control group/progressive/survival group (P<0.05); The APTT, TT, and PT levels in the observation group/complete/death group were lower than those in the control group (P<0.05); Among the factors that affect coagulation function and CysC levels, prognosis and disease type are independent risk factors (P<0.05).
Conclusion   The effectiveness of using CysC and coagulation function to diagnose ACI patients is good, which can provide valuable evidence for physicians in evaluating and analyzing the condition and prognosis.