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国际临床研究杂志

International Journal of Clinical Research

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International Journal of Clinical Research. 2023; 7: (5) ; 10.12208/j.ijcr.20230204 .

Clinical diagnosis and analysis of pathogens in acute respiratory tract infection
急性呼吸道感染病原体的临床检验诊断分析

作者: 刘占 *, 姜人铭

山东第一医科大学附属职业病医院(山东省职业病医院) 山东济南

*通讯作者: 刘占,单位:山东第一医科大学附属职业病医院(山东省职业病医院) 山东济南;

引用本文: 刘占, 姜人铭 急性呼吸道感染病原体的临床检验诊断分析[J]. 国际临床研究杂志, 2023; 7: (5) : 13-15.
Published: 2023/5/20 15:20:08

摘要

目的 分析急性呼吸道感染病原体的临床检验诊断。方法 选取我院收治的54例急性呼吸道感染患者设定为观察组,另选取同期70例体检健康者设定为对照组。采集两组的鼻咽分泌物及静脉血作为检验样本,通过聚合酶链反应(PCR)技术对两组的多种病原体进行检测。结果 观察组病原体检验结果明显高于对照组,差异均有统计学意义(P<0.05);观察组PCR、IFA、BLIT检验阳性结果均高于对照组,差异均有统计学意义(P<0.05)。但IgM检验阳性结果两组差异无统计学意义(P>0.05)。结论 急性呼吸道感染采用聚合酶链反应技术进行诊断效果显著,肺炎衣原体、肺炎支原体、柯萨奇病毒是引起患者急性呼吸道感染的重要病原体。

关键词: 急性呼吸道感染;病原体;临床检验

Abstract

Objective To analyze the clinical laboratory diagnosis of pathogens in acute respiratory tract infections.
Methods 54 patients with acute respiratory tract infection admitted to our hospital were selected as the observation group, and 70 healthy individuals who underwent physical examination during the same period were selected as the control group. Nasopharyngeal secretions and venous blood of the two groups were collected as test samples, and multiple pathogens of the two groups were detected by polymerase chain reaction (PCR).
Results The pathogen test results of the observation group were significantly higher than those of the control group, and the differences were statistically significant (P<0.05); The positive results of PCR, IFA, and BLIT tests in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). However, there was no statistically significant difference in the positive results of IgM test between the two groups (P>0.05).
Conclusion   The use of polymerase chain reaction technology for the diagnosis of acute respiratory tract infections has a significant effect. Chlamydia pneumoniae, Mycoplasma pneumoniae, and Coxsackie virus are important pathogens that cause acute respiratory tract infections in patients.

Key words: Acute respiratory tract infection; Pathogen; Clinical testing

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