Serum bilirubin and uric acid test were used for the clinical diagnosis of coronary heart disease
血清胆红素与尿酸检验用于冠心病临床诊断效果分析

摘要

目的 探究冠心病临床诊断中应用血清胆红素与尿酸检验的效果。方法 选择本院收治的冠心病患者作为研究对象（观察组），共计50例，收治时间为2020年1月至2021年12月。并择取同期前来本院体检的健康人士50例作为参照对象（对照组）。本院对两组对象均行血清胆红素、尿酸检验，同时对观察组患者行冠脉造影。比较两组血清胆红素、尿酸检验指标水平，并分析不同严重程度的冠心病对血清胆红素、尿酸检验指标水平影响。结果 观察组直接胆红素水平为（4.75±1.52）umoi/L、间接胆红素水平为（6.84±1.26）umoi/L、总胆红素水平水平为（11.54±4.03）umoi/L，低于对照组（P<0.05）；尿酸水平为（374.23±30.18）umoi/L，高于对照组。随病症严重程度提升，患者胆红素水平逐渐下降，尿酸水平逐渐提升（P<0.05）。结论冠心病临床诊断中应用血清胆红素、尿酸检验效果显著，可准确诊出病变，还能够为患者病变严重程度提供参考依据，值得推广。

Abstract

Objective To explore the effect of applying serum bilirubin and uric acid test in the clinical diagnosis of coronary heart disease.
Methods The 50 CAD patients were selected as the study subjects (observation group), and were admitted from January 2020 to December 2021. And 50 healthy patients who came to the hospital for physical examination were selected as the reference objects (control group). The hospital performed serum bilirubin and uric acid tests in both groups, and also performed coronary angiography for the patients in the observation group. The levels of serum bilirubin and uric acid test were compared between the two groups, and the influence of different severity of coronary heart disease on the levels of serum bilirubin and uric acid test was analyzed.
Results The direct bilirubin level in the observation group was (4.75 ± 1.52) umoi/L, the indirect bilirubin level was (6.84 ± 1.26) umoi/L, and the total bilirubin level was (11.54 ± 4.03) umoi/L, which was lower than that in the control group (P<0.05); The uric acid level was (374.23 ± 30.18) umoi/L, which was higher than the control group (P<0.05). As the severity of the disease increases, the patient's bilirubin level gradually decreases and uric acid level gradually increases.
Conclusion   The application of serum bilirubin and uric acid test in the clinical diagnosis of coronary heart disease is effective to confirm the lesions, and can also provide a reference for the severity of patients' lesions, which is worth popularizing.