Clinical application of end respiratory carbon monoxide (ETCO) in assessing the risk of Neonatal jaundice
呼吸末一氧化碳测定（ETCO）在评估新生儿黄疸风险的临床应用

摘要

目的 评估呼吸末一氧化碳测定（ETCO）在评估新生儿黄疸风险的临床应用。方法 应用医学实验对比法，选取2021年7月到2021年12月120例新生儿黄疸患儿，按照预测方法差异，分为对照组（n=60例）和实验组（n=60例），给予对照组常规血清学检查，给予实验组呼吸末一氧化碳测定（ETCO）测定，临床观察和比对两组患儿的临床应用价值。结果 实验组临床测定符合率95.00%（57/60）显著高于对照组临床测定符合率70.00%（42/60）明显，有统计学意义（P＜0.05）。实验组在预测新生儿黄疸风险上，显著优于对照组，凸显在应用后的灵敏度、特异性、准确率比之对照组更高，结果分别为（86.1±3.4）、（81.1±4.6）和（84.2±7.1）对比（78.4±5.2）、（73.2±3.5）和（75.4±5.3），有统计学意义（P＜0.05）。结论 呼吸末一氧化碳测定（ETCO）在评估新生儿黄疸风险的预测中，具有突出的测定效果，尤其可提高其临床测定符合率，并具有极高的灵敏度、特异性和准确率，可在临床实践中加以推广实施。

Abstract

Objetive To evaluate the clinical application of end respiratory carbon monoxide (ETCO) in assessing the risk of Neonatal jaundice.
Methods 120 cases of Neonatal jaundice from July 2021 to December 2021 were selected by the method of medical experiment comparison, and were divided into the control group (n=60 cases) and the experimental group (n=60 cases) according to the difference of prediction methods. Routine serological tests were given to the control group, and the end respiratory carbon monoxide (ETCO) test was given to the experimental group. The clinical application value of the two groups of children was observed and compared. The clinical measurement coincidence rate of 95.00% (57/60) in the experimental group was significantly higher than that of 70.00% (42/60) in the control group, with statistical significance (P<0.05). The experimental group was significantly better than the control group in predicting the risk of Neonatal jaundice, highlighting that the sensitivity, specificity and accuracy after application were higher than those of the control group. The results were (86.1 ± 3.4), (81.1 ± 4.6) and (84.2 ± 7.1), respectively (78.4 ± 5.2), (73.2 ± 3.5) and (75.4 ± 5.3), with statistical significance (P<0.05).
Conclusion   The measurement of end respiratory carbon monoxide (ETCO) has a prominent effect in predicting the risk of Neonatal jaundice, especially in improving the coincidence rate of clinical measurement, and has high sensitivity, specificity and accuracy, which can be popularized in clinical practice.