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国际临床研究杂志

International Journal of Clinical Research

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International Journal of Clinical Research. 2023; 7: (3) ; 10.12208/j.ijcr.20230139 .

Efficacy of valsartan combined with amlodipine in the treatment of hypertension with diabetes in community
缬沙坦结合氨氯地平治疗社区高血压合并糖尿病患者的有效性分析

作者: 范兵 *

深圳市龙岗区人民医院 广东深圳

*通讯作者: 范兵,单位:深圳市龙岗区人民医院 广东深圳;

引用本文: 范兵 缬沙坦结合氨氯地平治疗社区高血压合并糖尿病患者的有效性分析[J]. 国际临床研究杂志, 2023; 7: (3) : 129-132.
Published: 2023/3/25 14:32:31

摘要

目的 探讨在社区高血压合并糖尿病患者的治疗过程之中采取缬沙坦结合氨氯地平的治疗效果以及价值。方法 研究时间为2021年6月--2022年6月,选取在这个期间在我院收治的100例社区高血压合并糖尿病患者,分为研究组(缬沙坦结合氨氯地平治疗)和对照组(氨氯地平治疗),观察两组患者的临床治疗效果。结果 治疗后,两组患者的血压控制水平得到明显的改善,但研究组患者的改善更加优异,P<0.05;研究组的患者治疗有效率比对照组的患者高,P<0.05;治疗后,两组患者的血糖水平得到明显的改善,但研究组的改善更加优异,P<0.05;治疗后,两组患者的尿素氮、血尿酸以及血清膀胱抑素C的水平得到明显的改善,但研究组的高血压患者的改善更加优异,P<0.05。结论 在社区高血压合并糖尿病患者的治疗过程之中采取缬沙坦结合氨氯地平,可以有效的控制患者的血压水平,临床治疗效果理想,可以在临床上进行推广。

关键词: 缬沙坦;氨氯地平;高血压;糖尿病;效果评价

Abstract

Objective To explore the efficacy and value of valsartan combined with amlodipine in the treatment of hypertension with diabetes in the community.
Methods The study period was from June 2021 to June 2022. 100 patients with hypertension and diabetes in our hospital were selected and divided into the study group (valsartan combined with amlodipine) and the control group (amlodipine). The clinical therapeutic effects of the two groups were observed. After treatment, the blood pressure control levels of the two groups of patients were significantly improved, but the improvement in the study group was even better, P<0.05; The treatment effectiveness rate of patients in the study group was higher than that of patients in the control group, P<0.05; After treatment, the blood sugar levels of the two groups of patients were significantly improved, but the improvement in the study group was even better, P<0.05; After treatment, the levels of urea nitrogen, blood uric acid, and serum cystatin C in both groups of patients were significantly improved, but the improvement in the study group of hypertensive patients was even better, P<0.05.
Conclusion   Valsartan combined with amlodipine can effectively control the blood pressure level of patients with hypertension and diabetes in the community. The clinical treatment effect is ideal and can be popularized in clinical practice.

Key words: Valsartan; Amlodipine; hypertension; Diabetes; impact assessment

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