Clinical efficacy of metronidazole combined with cefaclor in the treatment of periodontitis
甲硝唑联合头孢克洛治疗牙周炎的临床疗效研究

摘要

目的 分析在对牙周炎患者进行治疗时按照甲硝唑、头孢克洛进行治疗的效果。方法 按照对比治疗观察的方式开展探究，纳入患者68例，时间段为2021年3月至2022年5月，按照双盲法均分为对照组（34例，常规方案治疗）和观察组（34例，甲硝唑+头孢克洛）进行治疗。对两组患者的恢复情况进行对比观察。结果 对两组在治疗期间牙周探诊深度、附着丧失、菌斑指数对比，在治疗前两组无差异，P>0.05，治疗后，观察组各指标均低于对照组，P<0.05。对比两组患者治愈时间，临床症状改善时间，观察组均短于对照组，P<0.05。对比两组治疗期间不良反应发生率，观察组发生率低于对照组，P<0.05。结论 临床在对牙周炎患者进行治疗时按照甲硝唑+头孢克洛进行治疗，可以促使患者对应症状得到改善，缩短患者康复时间且治疗期间患者不良反应少，用药安全性较高。

Abstract

Objective To analyze the effect of metronidazole and cefaclor in the treatment of periodontitis.
Methods According to the way of comparative treatment and observation, 68 patients were included in the study. The period was from March 2021 to May 2022. According to the double blind method, they were divided into the control group (34 cases, conventional treatment) and the observation group (34 cases, metronidazole+cefaclor) for treatment. The recovery of the two groups was observed.
Results There was no difference in periodontal probing depth, attachment loss and plaque index between the two groups before treatment (P>0.05). After treatment, all indexes in the observation group were lower than those in the control group (P<0.05). The cure time and clinical symptom improvement time of the two groups were compared. The observation group was shorter than the control group (P<0.05). The incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05).
Conclusion   The clinical treatment of periodontitis patients according to metronidazole+cefaclor can improve the corresponding symptoms of patients, shorten the recovery time of patients, reduce the adverse reactions of patients during the treatment, and have high drug safety.