Analysis and discussion on the effect of Huangqi Jianzhong Decoction on chronic gastritis of spleenand stomach deficiency cold type
黄芪建中汤治疗脾胃虚寒型慢性胃炎的效果分析与探讨

摘要

目的 分析对于慢性胃炎（脾胃虚寒型）患者通过采用中医药黄芪建中汤的治疗价值。方法 病例抽取时间为2020年1月～2022年4月，地点为我院，诊断结果均为慢性胃炎，中医证候分型为脾胃虚寒型，病例数量76例，借助随机数字表法分组，即对照组、观察组，均为38例，对照组为常规西药治疗，同期观察组进一步加用中医药黄芪建中汤进行治疗，对于2组患者的症状严重程度、症状消失时间、治疗总有效率、幽门螺杆菌（Hp）转阴率以及随访中疾病复发率等进行对比。结果 施治前各项中医症候评分及总积分2组做对比差异甚微P＞0.05，经施治与对照组相比各项中医症候评分及总积均为观察组更低P＜0.05；治疗总有效率比较中，观察组97.37%、对照组84.21%，P＜0.05；Hp转阴率比较中，观察组100.00%，对照组84.21%，P＜0.05；上腹疼痛、恶心呕吐、食欲减退、反酸以及餐后饱胀等症状消失时间均为观察组更短P＜0.05；疾病复发率比较中，观察组2.63%，对照组21.05%，P＜0.05。结论 对于慢性胃炎（脾胃虚寒型）患者采用中医药黄芪建中汤进行治疗可进一步提升临床疗效，有效改善临床症状并加快病情康复，且有助于清除Hp及降低复发率。

Abstract

Objective To analyze the therapeutic value of Huangqi Jianzhong Decoction for patients with chronic gastritis (spleen and stomach deficiency cold type). Method The cases were selected from January 2020 to April 2022 in our hospital. The diagnosis results were chronic gastritis, and the TCM syndrome type was spleen and stomach deficiency cold type. The number of cases was 76, which were divided by random number table method, i.e., control group and observation group, both 38 cases, and the control group was treated with conventional western medicine. At the same time, the observation group was further treated with traditional Chinese medicine Huangqi Jianzhong Decoction. The severity of symptoms, duration of symptom disappearance, total effective rate of treatment, negative conversion rate of Helicobacter pylori (Hp) and disease recurrence rate during follow-up were compared between the two groups.
Results Before treatment, there was little difference between the two groups in TCM symptom score and total score (P > 0.05). After treatment, compared with the control group, the TCM symptom score and total score were lower in observation group (P < 0.05). The total effective rate was 97.37% in the observation group and 84.21% in the control group, P < 0.05. The Hp negative conversion rate was 100.00% in the observation group and 84.21% in the control group, P < 0.05. The disappearance time of epigastric pain, nausea and vomiting, loss of appetite, acid reflux and postprandibular distention were all shorter in the observation group (P < 0.05). The recurrence rate was 2.63% in the observation group and 21.05% in the control group, P < 0.05.
Conclusion   For patients with chronic gastritis (spleen and stomach deficiency cold type), the use of TCM Huangqi Jianzhong decoction can further improve clinical efficacy, effectively improve clinical symptoms and accelerate the recovery of the disease, and help to eliminate Hp and reduce the recurrence rate.