Effect of norepinephrine on total hip replacement in elderly patients
去甲肾上腺素在老年全髋关节置换术中的效果

摘要

目的 探究分析去甲肾上腺素在老年全髋关节置换术中的效果。方法 选取于2021年1月至2022年1月，至我院接受老年全髋关节置换术的患者共108例，作为本次研究对象。根据患者的入院序列数为基础，采用随机数字分组的方式，将108例患者随机分为对照组以及观察组。对照组未采用去甲肾上腺素；观察组采用去甲肾上腺素。对比分析对照组以及观察组围手术期不良反应发生率；围手术期输液量以及不同时间点的平均动脉压与心率。结果 经干预完成后，观察组在围手术期不良反应发生率；围手术期输液量以及不同时间点的平均动脉压与心率方面明显优于对照组，其中（P＜0.05），差异具有统计学意义。结论 在对接受老年全髋关节置换术的患者进行干预的过程中，应用去甲肾上腺素进行干预，能够有效降低患者围手术期不良反应发生率，同时能够改善患者围手术期输液量以及不同时间点的平均动脉压与心率，在实际应用的过程中具有优良的效果，值得进一步的推广与应用。

Abstract

Objective: To investigate the effect of norepinephrine in total hip replacement in the elderly.
Methods: A total of 108 elderly patients who underwent total hip arthroplasty in our hospital from January 2021 to January 2022 were selected as the subjects of this study. Based on the number of admission sequences of patients, 108 patients were randomly divided into control group and observation group by random number grouping. The control group was treated without norepinephrine; The observation group used norepinephrine. The incidence of perioperative adverse reactions in the control group and the observation group were compared. Perioperative fluid volume and mean arterial pressure and heart rate at different time points.
Results: The incidence of adverse reactions in the perioperative period in the observation group; The perioperative infusion volume and mean arterial pressure and heart rate at different time points were significantly better than those in the control group, and the difference was statistically significant (P<0.05).
Conclusion  : The application of norepinephrine for elderly patients undergoing total hip arthroplasty can effectively reduce the incidence of perioperative adverse reactions, and at the same time improve the perioperative infusion volume and the average arterial pressure and heart rate at different time points, which has excellent effects in the process of practical application, which is worthy of further promotion and application.