[email protected]

国际临床研究杂志

International Journal of Clinical Research

您当前位置:首页 > 精选文章

International Journal of Clinical Research. 2023; 7: (2) ; 10.12208/j.ijcr.20230069 .

Effect of montelukast sodium chewable tablets combined with azithromycin in the treatment of severe pneumonia in children
孟鲁司特钠咀嚼片联合阿奇霉素治疗小儿重症肺炎的效果分析

作者: 王红均 *

河北中石油中心医院 河北廊坊

*通讯作者: 王红均,单位:河北中石油中心医院 河北廊坊;

引用本文: 王红均 孟鲁司特钠咀嚼片联合阿奇霉素治疗小儿重症肺炎的效果分析[J]. 国际临床研究杂志, 2023; 7: (2) : 72-74.
Published: 2023/2/28 19:10:45

摘要

目的 将孟鲁司特钠咀嚼片联合阿奇霉素应用在小儿重症肺炎治疗中,分析该联合治疗方法的效果。方法 选取本院在2020年2月-2021年2月期间收治的小儿重症肺炎患儿(n=86)为本次研究对象。采取随机数字表法分为参考组(n=43)及实验组(n=43),前者给予阿奇霉素治疗,后者采取孟鲁司特钠咀嚼片联合阿奇霉素治疗。比较两组治疗效果。结果 两组治疗有效率对比可见实验组高(P<0.05)。两组症状缓解时间及住院时间比较可见实验组短。两组不良反应发生率比较可见实验组低(P<0.05)。结论 在小儿重症肺炎治疗中采孟鲁司特钠咀嚼片联合阿奇霉素治疗效果确切,可提升患儿治疗有效率,可短时间内缓解患儿的相关症状,降低不良反应发生,进而缩短住院时间。建议此种方法在临床上推广。

关键词: 孟鲁司特钠;阿奇霉素;小儿重症肺炎;治疗有效率;症状缓解时间;住院时间;不良反应

Abstract

Objective: To analyze the effect of montelukast sodium chewable tablets combined with azithromycin in the treatment of severe pneumonia in children.
Methods: Children with severe pneumonia (n=86) admitted in our hospital from February 2020 to February 2021 were selected as the subjects of this study. Randomized number table method was used to divide into reference group (n=43) and experimental group (n=43). The former was treated with azithromycin, and the latter was treated with montelukast sodium chewable tablets combined with azithromycin. The therapeutic effects of the two groups were compared.
Results: The effective rate of the two groups was higher in the experimental group (P<0.05). The symptom relief time and hospitalization time of the two groups were shorter than those of the experimental group. The incidence of adverse reactions in the two groups was lower in the experimental group (P<0.05).
Conclusion  : In the treatment of severe pneumonia in children, montelukast sodium chewable tablets combined with azithromycin has a definite effect, which can improve the treatment efficiency of children, alleviate the related symptoms of children in a short time, reduce the occurrence of adverse reactions, and then shorten the hospital stay. It is suggested that this method be popularized in clinical practice.

Key words: Montelukast sodium; Azithromycin; Severe pneumonia in children; Effective rate of treatment; Symptom relief time; Hospital stay; Adverse reactions

参考文献 References

[1] 胡云婷,林洁如,苏丽端.孟鲁司特钠联合阿奇霉素治疗小儿肺炎支原体感染伴喘息临床疗效观察[J].吉林医学,2021,42(11):2692-2694.

[2] 赖颖瑜,傅鑫东,王超.阿奇霉素联合孟鲁司特钠治疗小儿肺炎支原体肺炎的临床效果[J].临床合理用药杂志,2021,14(26):138-140.

[3] 陈凯星,杜毓城,潘银芳.阿奇霉素联合孟鲁司特治疗小儿肺炎支原体肺炎的效果分析[J].黑龙江医药,2021, 34(04): 853-855.

[4] 严磊.孟鲁司特钠联合阿奇霉素对小儿支原体肺炎患者T淋巴细胞亚群和炎性因子的影响[J].中国当代医药,2021,28(23):138-144.

[5] 徐培丽.孟鲁司特钠咀嚼片联合阿奇霉素治疗小儿重症肺炎的效果分析[J].北方药学,2021,18(08):168-169.

[6] 李军.阿奇霉素序贯疗法联合孟鲁司特钠治疗小儿支原体肺炎的临床分析[J].医学食疗与健康,2021, 19(09): 69-70.

[7] 王梁聪,马金丽,陈玲珍,董威.孟鲁司特钠咀嚼片联合阿奇霉素治疗小儿重症肺炎的效果及对炎性因子的影响[J].中国妇幼保健,2020,35(02):278-280.

[8] 朱国鹏.孟鲁司特钠咀嚼片联合阿奇霉素干混悬剂治疗小儿支原体肺炎的临床效果分析[J].基层医学论坛, 2019, 23(11):1496-1498.