Clinical inquiry of the clonal evolution of myelodysplastic syndromes
骨髓增生异常综合征克隆演变的临床探究

摘要

骨髓增生异常综合征属于一种异质性且恶性克隆性的造血疾病，主要表现为外周血细胞减少、骨髓造血功能低下、单系或多系的骨髓发育不良，并有向急性髓系白血病进一步发展的风险。本文针对骨髓增生异常综合征及其克隆演变过程进行研究，并且针对疾病提出一些预防和治疗的措施，从而对患者的健康提供基本的保障。

Abstract

Myelodysplastic syndrome is a heterogeneous and malignant clonal hematopoietic disease, mainly manifested by reduced peripheral blood cells, low bone marrow hematopoiesis, single or multilineage bone marrow dysplasia, and the risk of further development to acute myeloid leukemia. This paper studies the myelodysplastic syndrome and its clonal evolution process, and proposes some prevention and treatment measures for the disease, so as to provide the basic guarantee for the health of patients.