Effect of dexmedetomidine combined with propofol on anesthesia recovery time in elderly patients undergoing painless gastroscopic anesthesia
右美托咪定联合丙泊酚在老年患者无痛胃镜麻醉中对麻醉苏醒时间的影响

摘要

目的 研究在老年患者无痛胃镜麻醉中采用右美托咪定联合丙泊酚后对麻醉苏醒时间的影响。方法选择本院 2021年6 月至2022年6月来我院进行无痛胃镜检查的老年患者80例进行临床观察。按照数字法随机分为对照组和研究组，各40例。对照组实施丙泊酚治疗，研究组在对照组的基础上，联合应用右美托咪定治疗，对比分析研究组与对照组不一样时间点生命指标（呼吸、心率、平均动脉压和血氧饱和度）水平变化，观察两组患者苏醒时间和定向力恢复时间。结果 研究组的苏醒时间和定向力恢复时间显著短于对照组（P＜0.5）。对照组和研究组患者生命指标进行对比，两组数据T1无明显差异，T2,T3和T4这三个时间，研究组的生命指标数据明显比对照组稳定（p<0.05）。结论 在老年患者无痛胃镜麻醉中，使用右美托咪定联合丙泊酚，麻醉效果好，患者适应度高，且生命指标平稳，在临床可以大力推广和应用。

Abstract

Objective: To study the effect of dexmedetomidine combined with propofol on the recovery time of anesthesia in elderly patients undergoing painless gastroscopic anesthesia.
Methods: Eighty elderly patients who underwent painless gastroscopy in our hospital from June 2021 to June 2022 were selected for clinical observation. According to the numerical method, they were randomly divided into control group and study group, 40 cases in each group. The control group was treated with propofol, and the study group was treated with dexmedetomidine on the basis of the control group. The changes of vital indicators (respiration, heart rate, mean arterial pressure and oxygen saturation) at different time points between the study group and the control group were compared and analyzed. The recovery time and directional force recovery time of the two groups were observed.
Results: The awakening time and the recovery time of orientation force in the study group were significantly shorter than those in the control group (P < 0.5). The vital indicators of patients in the control group and the study group were compared. There was no significant difference in T1 data between the two groups, while the vital indicators of patients in the study group were significantly more stable than those in the control group at T2,T3 and T4 (p<0.05).
Conclusion  : Dexmedetomidine combined with propofol in painless gastroscopic anesthesia in elderly patients has good anesthetic effect, high patient fitness, and stable vital indicators, which can be widely promoted and applied in clinical practice.