Clinical study on the therapeutic effect of light therapy on depression treatment
光照疗法对抑郁症治疗作用的临床的研究

摘要

光照疗法，简称光疗，通过在一定时间段内周期性地暴露于日光或特定强度和波长的人造光来实现特定治疗目的。1980年，临床研究首次报道光疗可以有效治疗抑郁症，但其具体机制尚不清楚。研究也表明，视网膜上接收来的人造光信号也可以显著影响人体大脑组织中的各种相关功能神经回路结构和某些神经信息递质，这就可能说是光疗的抗抑郁镇痛作用产生的机制。光疗仪的抗抑郁镇痛效果是受多种影响因素综合影响，不同剂量的光程序仪具有完全不同效果的双向抗抑郁作用。本文研究光照疗法对抑郁症的临床疗效，并总结了光照疗法治疗抑郁症的相关神经生物学机制。

Abstract

Illuminated therapy, or phototherapy, achieves specific therapeutic purposes by periodically exposing it to sunlight or artificial light of a certain intensity and wavelength over a certain period of time. In 1980, clinical studies first reported that phototherapy could be effective in treating depression, but the specific mechanisms remain unclear. Studies have also shown that artificial light signals received on the retina can also significantly affect various related functional neural circuit structures and certain neuroinformation transmitters in human brain tissues, which may be the mechanism of the antidepressant and analgesic effects of phototherapy. The antidepressant and analgesic effect of phototherapy instrument is influenced by a combination of many influencing factors, and different doses of photoprogrammer have completely different effects. This paper studies the clinical efficacy of light therapy in depression and summarizes the relevant neurobiological mechanisms of light therapy for depression.