To observe the effect of metformin on diabetes
二甲双胍治疗糖尿病的疗效观察

摘要

目的 观察二甲双胍治疗糖尿病的疗效。方法 研究时间选取2021年2月-2022年2月，研究对象为我院一年间接诊的糖尿病患者中随机抽取的88例，经数字随机交替排序法将其分为对照组与观察组，每组各44例。对照组单独使用阿卡波糖治疗，观察组则联合二甲双胍治疗，比较两组的血糖值[空腹血糖（FPG）、餐后2 h血糖（2hPG）、糖化血红蛋白（HbAlc）]，胰岛功能[胰岛β细胞（Homa-β）、胰岛素抵抗（Homa-IR）、C-肽释放值（FCP）]。结果 治疗后观察组FPG、2hPG、HbAlc低于对照组（P＜0.05）；观察组Homa-IR、FCP低于对照组，Homa-β高于对照组（P＜0.05）。结论 在糖尿病的临床常规用药治疗中联合二甲双胍治疗的疗效甚佳，可帮助患者稳定控制血糖水平，促进胰岛功能恢复，值得推广。

Abstract

Objectives To observe the effect of metformin on diabetes.
Methods: From February 2021 to February 2022, the research target was 88 cases of randomly extracted from diabetic patients in our hospital for a year. There are 44 cases in each group. The control group was treated with Akaba sugar separately, and the observation group was treated with two metformin. Compared with the blood sugar value of the two groups [fasting blood glucose (FPG), 2 H blood glucose (2HPG), glycated hemoglobin (HBALC)] β cells (HOMA-β), insulin resistance (HOMA-IR), C-peptide release value (FCP)].
Results: After treatment, the observation group FPG, 2HPG, and HBALC were lower than the control group (P <0.05); the Observation group Homa-IR and FCP were lower than the control group, and the HOMA-β was higher than the control group (P <0.05).
Conclusion  : In the treatment of diabetes clinical conventional medication treatment, the treatment of binochalin is very effective, which can help patients to stabilize blood glucose levels and promote islet function recovery, which is worth promoting.