Application of various blood purification equipment in patients with hyperlipidemic severe acute pancreatitis
多种血液净化装备在高脂血症性重症急性胰腺炎患者中的应用探讨

摘要

目的 分析多种血液净化装备在高脂血症性重症急性胰腺炎患者中的应用效果。方法 回顾性分析100例高脂血症性重症急性胰腺炎患者临床资料，治疗时间为2019年1月-2022年4月，随机分两组，A组采用血浆置换结合持续性血液滤过治疗，B组采用持续性血液滤过治疗，对比A组及B组的治疗结局。结果 A组患者症状改善时间远远短于B组，有统计学意义P<0.05。治疗前，A组患者临床指标接近于B组（P>0.05）；治疗3天后，A组与B组患者APACHEII评分、IL-6、CRP、血清TG水平均低于治疗前，且A组患者更低，有统计学意义(P<0.05)。结论 多种血液净化装备在高脂血症性重症急性胰腺炎患者中的应用效果更明显，值得广泛利用。

Abstract

Objective To analyze the application effect of various blood purification equipment in patients with hyperlipidemic severe acute pancreatitis.
Methods the clinical data of 100 patients with hyperlipidemic severe acute pancreatitis were analyzed retrospectively. The treatment period was from January 2019 to April 2022. They were randomly divided into two groups. Group A was treated with plasma exchange combined with continuous hemofiltration, and Group B was treated with continuous hemofiltration. The treatment outcomes of Group A and Group B were compared.
Results the improvement time of symptoms in group A was significantly shorter than that in group B (P < 0.05). Before treatment, the clinical indexes of group A were close to those of group B (P > 0.05); After 3 days of treatment, Apache Ⅱ score, IL-6, CRP and serum TG levels of patients in group A and B were lower than those before treatment, and those in group A were lower (P < 0.05).
Conclusion   the application of various blood purification equipment in patients with hyperlipidemic severe acute pancreatitis is more effective and worthy of extensive use.