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国际医学与数据杂志

International Journal of Medicine and Data

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International Journal of Medicine and Data. 2022; 6: (5) ; 10.12208/j. ijmd.20220212 .

Effect of intraperitoneal thermoperfusion chemotherapy on gastrointestinal function and immune functionin patients with advanced gastric cancer
腹腔热灌注化疗对晚期胃癌患者胃肠道功能和免疫功能的影响

作者: 苗妍 *

西京医院 陕西西安

*通讯作者: 苗妍,单位:西京医院 陕西西安;

引用本文: 苗妍 腹腔热灌注化疗对晚期胃癌患者胃肠道功能和免疫功能的影响[J]. 国际医学与数据杂志, 2022; 6: (5) : 95-97.
Published: 2022/10/20 15:18:26

摘要

对晚期胃癌的患者予以腹腔热灌注化疗,分析对其免疫功能、胃肠道功能影响探究。方法:选取我院2020年9月1日至2022年9月1日期间诊治的40例患者参与研究,将其分为两组,研究组予以腹腔热灌注,对照组予以等量生理盐水灌注,每组患者20例,比较两组免疫功能、胃肠道反应等。结果:研究组免疫功能指标改善效果优于对照组,研究组胃肠道功能恢复效果优于对照组,临床对比具备统计学差异,(P<0.05)。结论:临床救治胃癌患者晚期症状期间予以腹腔热灌注化疗,具有极高的临床应用价值,能够有效改善患者免疫功能,促进胃肠道功能恢复,减少并发症发生,提高患者生存质量,值得临床推广使用。

关键词: 免疫功能;胃肠道功能;腹腔热灌注化疗

Abstract

to analyze the effect of intraperitoneal hyperthermic perfusion chemotherapy on immune function and gastrointestinal function of patients with advanced symptoms of gastric cancer.
Methods: 40 patients diagnosed and treated in our hospital were selected to participate in the study, and they were divided into groups according to chemotherapy methods. The study group received intraperitoneal hyperthermic perfusion chemotherapy, and the control group received normal saline perfusion. There were 20 patients in each group. The immune function, gastrointestinal Road reaction etc.
Results:The improvement effect of immune function indicators in the study group was better than that in the control group, and the recovery effect of gastrointestinal function in the study group was better than that in the control group, and the clinical comparison was statistically significant (P<0.05).
Conclusion  : Intraperitoneal hyperthermic perfusion chemotherapy during the clinical treatment of advanced symptoms of gastric cancer patients has extremely high clinical application value, can effectively improve the immune function of patients, promote the recovery of gastrointestinal function, reduce the occurrence of complications, and improve the quality of life of patients, which is worthy of clinical promotion.

Key words: immune function; Gastrointestinal function; Intraperitoneal thermoperfusion chemotherapy

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