Blood glucose concentration, cystatin C combined with 24h urine protein detection in diabetic patients withrenal failure Effectiveness evaluation
血糖浓度，胱抑素C联合24h尿蛋白检测应用于糖尿病合并肾功能衰竭中的有效性评价

摘要

目的 探讨血糖浓度，胱抑素C联合24h尿蛋白检测在糖尿病合并肾功能衰竭中的应用效果与诊断价值。方法 分别将2021年1月－2022年6月期间我院收治的糖尿病、糖尿病肾病、糖尿病肾衰竭病人各30例纳入研究A组、B组、C组，同期行健康体检受检者30例纳入健康组，并均进行血糖浓度，胱抑素C、24h尿蛋白指标水平检测，然后分析三项指标诊断糖尿病合并肾功能衰竭的效果。结果 研究C组血糖浓度，胱抑素C、24h尿蛋白指标水平检测结果均＞研究B组＞研究A组＞健康组，对比均有统计学意义（P<0.05）。在糖尿病合并肾功能衰竭中的阳性检出率上，联合检验较3项指标单独检验更高，对比均有统计学意义（P＜0.05）；但3项指标单独检验阳性检出率差异较小，对比无统计学意义（P＞0.05）。结论 血糖浓度，胱抑素C、24h尿蛋白指标水平可为糖尿病合并肾功能衰竭疾病进展程度提供有效参考，并增加疾病阳性检出率，对疾病“早发现、早诊断、早干预”奠定良好基础，值得被进一步推广应用。

Abstract

Objective To investigate the application effect and diagnostic value of cystatin C combined with blood glucose concentration and 24h urine protein test in diabetes combined with renal failure. Method respectively during January 2021-June 2022 during our hospital of diabetes, diabetes nephropathy, diabetic kidney failure patients each 30 cases in the study group A, group B, group C, during the health examination subjects 30 cases in health group, and blood glucose concentration, cystatin C, 24h urinary protein index level, and then analyze the effect of three indicators of diabetes with renal failure.
Results Blood glucose concentration in study group C, cystatin C and 24h urinary protein index levels were measured for all the results> study group B> study group A> healthy group (P <0.05). Regarding the positive detection rate in diabetes and renal failure, the combined test was higher than the three indicators alone, respectively (P <0.05), but the difference was small, with no statistical significance (P> 0.05).
Conclusion   Blood glucose concentration, cystatin C and 24h urinary protein index level can provide an effective reference for the disease progression degree of diabetes combined with renal failure, and increase the disease positive detection rate, and lay a good foundation for "early detection, early diagnosis and early intervention", which deserves further promotion and application.