Effect of salbutamol and budesonide on acute attack of chronic bronchitis
沙丁胺醇与布地奈德治疗慢性支气管炎急性发作的效果

摘要

目的 观察对慢性支气管炎急性发作患者施以布地奈德、沙丁胺醇治疗的效果。方法 观察对象选择于2021.1~2022.6就诊于我院的慢性支气管炎急性发作患者50例，随机抽签法施以分组观察，施以沙丁胺醇单用疗法的25例患者分入对照组，施以布的奈德、沙丁胺醇联用疗法的25例患者分入试验组，对治疗效果进行对比和观察。结果 与对照组患者（68.00%）比较，临床治疗效果试验组（96.00%）明显较高（P<0.05）；治疗前心率和呼吸频率2组比较（P>0.05）；比较对照组患者，心率和呼吸频率治疗后试验组明显较好（P<0.05）；比较对照组患者，临床症状（哮鸣音、湿啰音、气喘、咳嗽）消失时间试验组明显较短（P<0.05）。结论 对慢性支气管炎急性发作患者施以布地奈德、沙丁胺醇治疗效果突出，在临床疗效、心率、呼吸频率、临床症状消失方面优势明显，建议推广。

Abstract

Objective: To observe the effect of budesonide and salbutamol on patients with acute attack of chronic bronchitis.
Methods: 70 patients with acute attack of chronic bronchitis who were treated in our hospital from April 2021 to April 2022 were selected for observation. 35 patients treated with salbutamol alone were divided into the control group and 35 patients treated with budesonide and salbutamol combined were divided into the experimental group. The therapeutic effects were compared and observed.
Results: the blood gas analysis indexes (PaCO2, PaO2, SpO2) of the two groups before treatment were p>0.05. Compared with the patients in the control group, the blood gas analysis indexes of the experimental group were significantly better after treatment (p<0.05); Before treatment, heart rate and respiratory rate were compared between the two groups (p>0.05); Compared with the patients in the control group, the heart rate and respiratory rate in the experimental group were significantly better after treatment (p<0.05); Compared with the patients in the control group, the disappearance time of clinical symptoms (wheezing, moist rale, asthma, cough) in the test group was significantly shorter (p<0.05).
Conclusion  : Budesonide and salbutamol are effective in the treatment of patients with acute attack of chronic bronchitis. They have obvious advantages in blood gas analysis indicators, heart rate, respiratory rate and the disappearance of clinical symptoms. It is recommended to promote them.