Clinical effect of continuous blood purification on severe pancreatitis
连续性血液净化治疗重症胰腺炎的临床效果观察

摘要

目的 研究连续性血液净化治疗重症胰腺炎的临床效果。方法 选择2021年12月－2022年07月到本院治疗重症胰腺炎患者共72例作为观察对象，随机分为实验和对照两组，分析不同治疗方式的效果。结果 实验组血流动力学指标均优于对照组（P＜0.05）；治疗前，两组炎性因子（IL-6、TNF-a、IL-1、IL-8）、APACHEII评分对比（P＞0.05）；治疗后，实验组炎性因子（IL-6、TNF-a、IL-1、IL-8）水平与APACHEII评分低于对照组（P＜0.05）；实验组不良反应发生率4/36（11.11%）明显低于对照组15/36（41.67%）（P＜0.05）。结论 运用连续性血液净化治疗重症胰腺炎安全性和疗效均比较高，可推广运用。

Abstract

Objective:: To study the clinical effect of continuous blood purification on severe pancreatitis.
Methods: a total of 72 patients with severe pancreatitis treated in our hospital from December 2021 to July 2022 were randomly divided into experimental and control groups to analyze the effects of different treatment methods.
Results: the hemodynamic indexes of the experimental group were better than those of the control group (P < 0.05); Before treatment, the inflammatory factors (IL-6, TNF-a, IL-1, IL-8) and APACHE II scores of the two groups were compared (P > 0.05); After treatment, the levels of inflammatory factors (IL-6, TNF-a, IL-1, IL-8) and APACHE II scores in the experimental group were lower than those in the control group (P < 0.05); The incidence of adverse reactions in the experimental group (4 / 36) (11.11%) was significantly lower than that in the control group (15 / 36) (41.67%) (P < 0.05).
Conclusion  : continuous blood purification is safe and effective in the treatment of severe pancreatitis, which can be popularized.