Effects of fluconazole combined with corneal debridement on the recovery of visual acuity and corneal symptoms in patients with fungal keratitis
氟康唑联合角膜清创术对真菌性角膜炎患者视力及角膜症状恢复的影响

摘要

目的 分析在真菌性角膜炎患者治疗中，氟康唑联合角膜清创术对患者视力及角膜症状恢复的影响。方法 选取2020年5月－2022年5月收治的60例真菌性角膜炎患者，采用随机数字表法进行分组，即对照组30例，实行角膜清创术，观察组30例，实行氟康唑联合角膜清创术治疗，比较两组实施效果。结果 较对照组，观察组有效率高，P＜0.05；较对照组，观察组角膜愈合时间短、溃疡面积小、手术次数少，且视力恢复较好，P＜0.05；较对照组，观察组并发症发生率低，P＜0.05。结论 氟康唑联合角膜清创术在真菌性角膜炎患者治疗中效果显著，既能改善患者角膜症状，促进视力恢复，又能降低并发症，提高有效率。

Abstract

Objective: To analyze the effect of fluconazole combined with corneal debridement on the recovery of vision and corneal symptoms in patients with fungal keratitis.
Methods: A total of 60 patients with fungal keratitis who were treated from May 2020 to May 2022 were selected and grouped by random number table method, that is, 30 cases in the control group were treated with corneal debridement, and 30 cases in the observation group were treated with flucon azole combined with corneal debridement, and the effect of the two groups was compared.
Results: Compared with the control group, the observation group had a higher effective rate, P<0.05; compared with the control group, the observation group had shorter corneal healing time, smaller ulcer area, fewer operations, and better visual acuity recovery, P<0.05; compared with the control group, the observation group The incidence of complications in the group was lower, P<0.05.
Conclusion  : Fluconazole combined with corneal debridement has a significant effect in the treatment of fungal keratitis, which can not only improve the corneal symptoms of patients, promote the recovery of vision, but also reduce complications and improve the effective rate.