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国际临床研究杂志

International Journal of Clinical Research

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International Journal of Clinical Research. 2022; 6: (7) ; 10.12208/j.ijcr.20220304 .

Study on executive function in children with epileptic attention deficit and hyperactivity disorder (ADHD)
癫痫共患注意缺陷与多动障碍(ADHD)患儿执行功能的研究

作者: 刘美燕, 王荣 *

承德医学院 河北承德

沧州市人民医院儿科 河北沧州

*通讯作者: 王荣,单位:沧州市人民医院儿科 河北沧州;

收录截图(CNKI-Scholar)

引用本文: 刘美燕, 王荣 癫痫共患注意缺陷与多动障碍(ADHD)患儿执行功能的研究[J]. 国际临床研究杂志, 2022; 6: (7) : 48-52.
Published: 2022/9/7 14:05:04

摘要

癫痫(Epilepsy)是儿童时期最常见的神经系统疾病之一,其病因复杂、表现形式多样,常导致患者执行功能障碍。ADHD不仅是儿童常见的神经发育性疾病还是癫痫最常见的共患病之一。共患病的存在加重了疾病的诊治困难,还对患者的执行功能产生更为严重的影响。本文将对癫痫、ADHD以及癫痫共患ADHD对患者执行功能的损害进行综述。

关键词: 癫痫;ADHD;共患病;执行功能

Abstract

Epilepsy is one of the most common neurological diseases in children,It has complex etiology and various manifestations, and often leads to executive dysfunction.ADHD is a common neurodevelopmental disorder in children but also one of the most common comorbidities of epilepsy. Presence of comorbidities aggravates the difficulty of diagnosis and treatment of the disease,and causes more serious damage to the patients' executive function.This paper will review the impairment of epilepsy,ADHD and epileptic comorbid ADHD to patients' executive function.

Key words: Epilepsy; ADHD; Comorbidity; Executive Function

参考文献 References

[1] Thurman David J, Beghi Ettore, Begley Charles E et al. Standards for epidemiologic studies and surveillance of epilepsy.[J].Epilepsia,2011,null:2-26. 

[2] Ngugi Anthony K, Bottomley Christian, Kleinschmidt Immo et al. Estimation of the burden of active and life- time epilepsy: a meta-analytic approach.[J]. Epilepsia, 2010,51:883-90. 

[3] Aaberg Kari Modalsli, Bakken Inger Johanne,Lossius Morten I et al. Comorbidity and Childhood Epilepsy:A Nationwide Registry Study. [J]. Pediatrics,2016 Sep; 138(3): e20160921. 

[4] Cohen Rony,Senecky Yehuda,Shuper Avinoam et al. Prevalence of epilepsy and attention-deficit hyperactivity (ADHD) disorder:a population-based study.[J].J Child Neurol,2013,28:120-3. 

[5] Vidaurre Jorge,Twanow Jaime Dawn E,Attention Deficit Hyperactivity Disorder and Associated Cognitive Dysfunction in Pediatric Epilepsy.[J].Semin Pediatr Neurol, 2017, 24: 282-291. 

[6] Loe Irene M,Kakar Pooja A,Sanders Lee M,Diagnosis, Evaluation, and Treatment of Attention- Deficit/ Hyperactivity Disorder.[J].JAMA Pediatr, 2021, 175: 191-192. 

[7] Battle Dolores Elaine, Diagnostic and Statistical Manual of Mental Disorders (DSM).[J].Codas,2013,25:191-2. 

[8] Baddeley A. Working memory: theories, models, and controversies.Annu Rev Psychol. 2012;63:1-29. 

[9] Wiemers Elizabeth A,Redick Thomas S,Working memory capacity and intra-individual variability of proactive control.[J].Acta Psychol (Amst),2018,182:21-31. 

[10] Fiske Abigail,Holmboe Karla,Neural substrates of early executive function development.[J].Dev Rev, 2019, 52: 42-62. 

[11] Sarah A.Healy,Nancie Im-Bolter,Janet Olds.Executive Function and Emotional,Behavioral, and Social Competence Problems in Children with Epilepsy[J]. Journal of Child and Family Studies, 2018, 27(8): 2430-2440. 

[12] Roca María, Parr Alice, Thompson Russell et al. Executive function and fluid intelligence after frontal lobe lesions. [J]. Brain,2010,133:234-47. 

[13] Park Chang-Hyun, Choi Yun Seo, Kim Hyeon Jin et al. Interactive effects of seizure frequency and lateralization on intratemporal effective connectivity in temporal lobe epilepsy.[J] .Epilepsia,2018,59:215-225. 

[14] Campiglia M, Seegmuller C,Le Gall D et al.Assessment of everyday executive functioning in children with frontal or temporal epilepsies.[J].Epilepsy Behav,2014,39:12-20. 

[15] Law Nicole,Widjaja Elysa,Smith Mary Lou,Unique and shared areas of cognitive function in children with intractable frontal or temporal lobe epilepsy.[J].Epilepsy Behav,2018,80: 157-162. 

[16] Modi Avani C,Vannest Jennifer,Combs Angela et al. Pattern of executive functioning in adolescents with epilepsy: A multimethod measurement approach. [J] . Epilepsy Behav, 2018, 80:5-10. 

[17] Vinayan KP, Biji V, Thomas SV. Educational problems with underlying neuropsychological impairment are common in children with Benign Epilepsy of Childhood with Centrotemporal Spikes (BECTS).Seizure.2005 Apr;14(3):207-12. 

[18] Genizi Jacob, Shamay-Tsoory Simone G,Shahar Eli et al.Impaired social behavior in children with benign childhood epilepsy with centrotemporal spikes.[J].JChild Neurol,2012,27: 156-61. 

[19] Cheng Dazhi, Yan Xiuxian,Gao Zhijie et al. Common and Distinctive Patterns of Cognitive Dysfunction in Children With Benign Epilepsy Syndromes.[J].Pediatr Neurol, 2017, 72:36-41. 

[20] Jun Ye-Hwa,Eom Tae-Hoon,Kim Jung-Min,Concomitance of benign epilepsy with centrotemporal spikes and childhood absence epilepsy: an unusual case.[J].Neurol Sci, 019,40:1979-1980. 

[21] Kucukboyaci N Erkut,Girard H M,Hagler D J et al.Role of frontotemporal fiber tract integrity in task-switching performance of healthy controls and patients with temporal lobe epilepsy.[J].J Int Neuropsychol Soc, 2012, 18:57-67. 

[22] Keller Simon Sean, Baker Gus,Downes Joseph John et al. Quantitative MRI of the prefrontal cortex and executive function in patients with temporal lobe epilepsy.[J]. Epilepsy Behav, 2009,15:186-95. 

[23] Deltour Laëtitia,Quaglino Véronique,Barathon Marion et al. Clinical evaluation of attentional processes in children with benign childhood epilepsy with centrotemporal spikes (BCECTS).[J].Epileptic Disord,2007,9:424-31.  

[24] Malfait D,Tucholka A,Mendizabal S et al.fMRI brain response during sentence reading comprehension in children with benign epilepsy with centro-temporal spikes.[J]. Epilepsy Res,2015,117:42-51. 

[25] Li Yihan,Sun Yulei, Zhang Tingting et al. The relationship between epilepsy and cognitive function in benign childhood epilepsy with centrotemporal spikes.[J] .Brain Behav, 2020,10:e01854. 

[26] Ciumas Carolina,S aignavongs Mani,Ilski Faustine et al.White matter development in children with benign childhood epilepsy with centro-temporal spikes.[J]. Brain, 2014, 137:1095-106. 

[27] Cerminara Caterina, D'Agati Elisa, Lange Klaus W et al.Benign childhood epilepsy with centrotemporal spikes and the multicomponent model of attention: a matched control study.[J].Epilepsy Behav,2010,19:69-77. 

[28] Parrish Joy,Geary Elizabeth,Jones Jana et al.Executive functioning in childhood epilepsy:parent-report and cognitive assessment.[J].Dev Med Child Neurol,2007,49:412-6. 

[29] Modi Avani C,Gutierrez-Colina Ana M,Wagner Janelle L et al.Executive functioning phenotypes in youth with epilepsy.[J].Epilepsy Behav,2019, 90:112-118. 

[30] Xia Shugao,Li Xiaobo,Kimball Ariane E et al.Thalamic shape and connectivity abnormalities in children with attention-deficit/hyperactivity disorder.[J].Psychiatry Res, 2012, 204:161-7. 

[31] Hart Heledd, Radua Joaquim, Nakao Tomohiro et al. Meta- analysis of functional magnetic resonance imaging studies of inhibition and attention in attention- deficit /hyperactivity disorder:exploring task-specific,stimulant medication, and age effects.[J].J AMA Psychiatry, 2013, 70:185-98. 

[32] Thaler Nicholas S, Bello Danielle T, Etcoff Lewis M,WISC-IV profiles are associated with differences in symptomatology and outcome in children with ADHD.[J] .J Atten Disord, 2013,17:291-301. 

[33] Barkley Russell A, Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD.[J] .Psychol Bull,1997,121:65-94. 

[34] Kerns KA, McInerney RJ, Wilde NJ. Time reproduction, working memory, and behavioral inhibition in children with ADHD. Child Neuropsychol.2001 Mar;7(1):21-31. 

[35] Tan Alexander, Delgaty Lauren, Steward Kayla et al. Performance- based measures and behavioral ratings of executive function in diagnosing attention-deficit/ hyperactivity disorder in children.[J].Atten Defic Hyperact Disord,2018,10:309-316. 

[36] Gioia Gerard A,Isquith Peter K,Kenworthy Lauren et al. Profiles of everyday executive function in acquired and developmental disorders.[J].Child Neuropsychol, 2002, 8:121-37. 

[37] McCandless Stephen,O' Laughlin Liz,The Clinical Utility of the Behavior Rating Inventory of Executive Function (BRIEF) in the diagnosis of ADHD.[J].J Atten Disord, 2007, 10: 381-9. 

[38] Bauer Brian W,Gustafsson Hanna C, Nigg Joel et al. Working memory mediates increased negative affect and suicidal ideation in childhood attention-deficit/ hyperactivity disorder.[J]. J Psychopathol Behav Assess, 2018, 40:180-193. 

[39] Krieger Virginia, Amador-Campos Juan Antonio, Gallardo- Pujol David, Temperament, executive function, and attention-deficit/hyperactivity disorder(ADHD)in adolescents: The mediating role of effortful control.[J].J Clin Exp Neuropsychol,2019,41:615-633. 

[40] Skogli Erik Winther,Egeland Jens,Andersen Per Normann et al.Few differences in hot and cold executive functions in children and adolescents with combined and inattentive subtypes of ADHD.[J].Child Neuropsychol, 2014, 20: 162-81. 

[41] Coghill D R, Seth S, Matthews K,A comprehensive assessment of memory, delay aversion, timing, inhibition, decision making and variability in attention deficit hyperactivity disorder: advancing beyond the three- pathway models.[J]. Psychol Med, 2014, 44: 1989-2001. 

[42] MacAllister William S, Vasserman Marsha,Vekaria Pooja et al. Neuropsychological endophenotypes in ADHD with and without epilepsy.[J].Appl Neuropsychol Child, 2012, 1:121-8. 

[43] Kang Sung-Han,Yum Mi-Sun,Kim Eun-Hee et al. Cognitive function in childhood epilepsy:importance of attention deficit hyperactivity disorder.[J].J Clin Neurol, 2015, 11:20-5. 

[44] Liu Shu-Tsen,Tsai Fang-Ju,Lee Wang-Tso et al.Attentional processes and ADHD-related symptoms in pediatric patients with epilepsy.[J].Epilepsy Res, 2011,93:53-65. 

[45] 陈静,周农,刘天龙,顾安丽,陈晓霞.癫痫共患ADHD儿童的生态学执行功能[J].安徽医科大学学报,2015,50(09): 1301-1305. 

[46] Lima Ellen M,Rzezak Patricia,Guimarães Catarina A et al. The executive profile of children with Benign Epilepsy of Childhood with Centrotemporal Spikes and Temporal Lobe Epilepsy.[J].Epilepsy Behav,2017,72:173-177. 

[47] 房海波,王荣,褚琳娜,等.伴中央颞区棘波的儿童良性癫痫共患注意缺陷多动障碍患儿认知功能损害的前瞻性研究[J].中国当代儿科杂志,2021,23(8):791-796.