Effect of non-invasive intermittent positive pressure ventilation on respiratory support after weaning in neonatal respiratory distress syndrome
无创间歇正压通气对新生儿呼吸窘迫综合征撤机后呼吸支持的效果

摘要

目的 分析无创间歇正压通气对新生儿呼吸窘迫综合征撤机后呼吸支持的效果。方法 此次实验对象为新生儿呼吸窘迫综合征患儿，入院时间均在2020.04月至2022.04月，入选患儿总共82例，利用红绿双色球法进行分组，分为对照组（经鼻持续正压通气治疗，n=41）与实验组（无创间歇正压通气治疗，n=41）。对比分析两组的血气指标、治疗效果、撤机情况及并发症发生情况。结果 在二氧化碳分压（PaCO2）、血氧饱和度（SaO2）及氧分压（PaO2）上，实验组优于对照组（P＜0.05）。在用氧时长、通气时长及住院天数上，实验组均短于对照组（P＜0.05）。在撤机成功率上，实验组高于对照组；在并发症发生率上，实验组低于对照组（P＜0.05）。结论 对新生儿呼吸窘迫综合征患儿实施无创间歇正压通气治疗后，对于改善血气指标具有促进作用，临床可进一步推广应用。

Abstract

Objective To analyze the effect of non-invasive intermittent positive pressure ventilation on respiratory support after weaning of neonatal respiratory distress syndrome.
Methods: The subjects of this experiment were children with neonatal respiratory distress syndrome. The admission time was from April 2020 to April 2022. A total of 82 children were selected. They were grouped by the red and green two-color ball method and divided into a control group (continuous normal nasal passage). pressure ventilation therapy, n=41) and the experimental group (non-invasive intermittent positive pressure ventilation therapy, n=41). The blood gas indexes, treatment effect, weaning situation and complications were compared and analyzed between the two groups.
Results: The experimental group was better than the control group in terms of carbon dioxide partial pressure (PaCO2), blood oxygen saturation (SaO2) and oxygen partial pressure (PaO2) (P<0.05). The experimental group was shorter than the control group in terms of oxygen use time, ventilation time and hospitalization days (P<0.05). The success rate of weaning in the experimental group was higher than that in the control group; the incidence of complications in the experimental group was lower than that in the control group (P<0.05).
Conclusion  : The non-invasive intermittent positive pressure ventilation for infants with neonatal respiratory distress syndrome can promote the improvement of blood gas indexes, and it can be further popularized and applied in clinical practice.