Effects of sitagliptin combined with metformin on islet function and epicardial adipose tissue thickness in obese diabetes
西格列汀联合二甲双胍对肥胖型糖尿病胰岛功能和心外膜脂肪组织厚度的影响分析

摘要

目的 研究西格列汀联合二甲双胍对肥胖型糖尿病胰岛功能和心外膜脂肪组织厚度的影响。方法 选择2021年01月－2022年01月到本院收治的肥胖型糖尿病患者76例，按照不同治疗方式分作实验组和对照组，分析治疗效果。结果 治疗前，两组胰岛功能、EAT厚度组间对比，P＞0.05；治疗后，实验组胰岛功能、EAT厚度均优于对照组，P＜0.05。结论 运用西格列汀联合二甲双胍方式治疗肥胖型糖尿病患者，效果显著，能够改善其胰岛功能、心外膜脂肪组织厚度，具有一定的临床价值。

Abstract

Objective: To study the effects of sitagliptin combined with metformin on islet function and epicardial adipose tissue thickness in obese diabetes.
Methods: 76 obese patients with diabetes admitted to our hospital from January 2021 to January 2022 were divided into experimental group and control group according to different treatment methods, and the treatment effects were analyzed.
Results: before treatment, the islet function and eat thickness of the two groups were compared (P > 0.05); After treatment, the islet function and eat thickness of the experimental group were better than those of the control group (P < 0.05).
Conclusion  : cigliptin combined with metformin is effective in the treatment of obese patients with diabetes, which can improve their islet function and epicardial adipose tissue thickness.